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Tdark
LDLRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371360
  • ENSP00000360411
  • ENSG00000203985
  • ENST00000371362
  • ENSP00000360413
  • ENST00000420619
  • ENSP00000411017
  • ENST00000545928
  • ENSP00000445871
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.45
cell line
0.42
transcription factor
0.42
phenotype
0.33
interacting protein
0.31


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.72   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.72   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (15)
OR10S1
Tdark
Family:  oGPCR
Novelty:  2.23425255
Score:  0.648
Data Source:  STRINGDB
MSANTD1
Tdark
Novelty:  4.11977517
Score:  0.587
Data Source:  STRINGDB
MANSC1
Tdark
Novelty:  0.91681036
Score:  0.585
Data Source:  STRINGDB
SLCO1B7
Tdark
Family:  Transporter
Novelty:  0.48557976
Score:  0.571
Data Source:  STRINGDB
TCEANC2
Tdark
Novelty:  0.40325323
Score:  0.57
Data Source:  STRINGDB
LCE1A
Tbio
Novelty:  0.04596696
Score:  0.531
Data Source:  STRINGDB
AP3S2
Tdark
Novelty:  0.25186243
Score:  0.477
Data Source:  STRINGDB
FGFBP3
Tbio
Novelty:  0.25896399
Score:  0.463
Data Source:  STRINGDB
TMEM59
Tbio
Novelty:  0.0329414
Score:  0.45
Data Source:  STRINGDB
TPTE2
Tbio
Family:  Enzyme
Novelty:  0.04710658
Score:  0.444
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
thyroxine measurement
1
1
1
81.1
hormone measurement
1
1
3
80.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
thyroxine measurement
1
81.1
hormone measurement
3
80.4
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
low density lipoprotein receptor class A domain containing 1
716707
Mouse
MGI:3652166
546840
Rat
RGD:1597398
689088
Dog
low density lipoprotein receptor class A domain containing 1
VGNC:42623
610617
Horse
low density lipoprotein receptor class A domain containing 1
VGNC:19622
100060633
Species
Name
OMA
EggNOG
Inparanoid
Macaque
low density lipoprotein receptor class A domain containing 1
Mouse
Rat
Dog
low density lipoprotein receptor class A domain containing 1
Horse
low density lipoprotein receptor class A domain containing 1
Publication Statistics
PubMed Score 0.72
PubMed score by year
PubTator Score 0.41
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title