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Tbio
ADGRF1
Adhesion G-protein coupled receptor F1

Protein Summary
Description
Orphan receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371243
  • ENSP00000360289
  • ENSG00000153292
  • ENST00000371253
  • ENSP00000360299

Symbol
  • GPR110
  • PGR19
  • PGR19
  • GPR110
  • KPG_012
  • hGPCR36
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.95
gene perturbation
0.75
microRNA
0.73
protein domain
0.73
cell type or tissue
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 176   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 176   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
GPR141
Tdark
Family:  GPCR
Novelty:  0.30711523
Score:  0.721
Data Source:  STRINGDB
GPR139
Tchem
Family:  GPCR
Novelty:  0.04083224
Score:  0.716
Data Source:  STRINGDB
PTGER1
Tclin
Family:  GPCR
Novelty:  0.0013716
Score:  0.682
Data Source:  STRINGDB
GPR148
Tbio
Family:  GPCR
Novelty:  0.019374
Score:  0.672
Data Source:  STRINGDB
SSTR4
Tclin
Family:  GPCR
Novelty:  0.01528237
Score:  0.653
Data Source:  STRINGDB
ADGRA1
Tbio
Family:  GPCR
Novelty:  0.24926468
Score:  0.645
Data Source:  STRINGDB
PPRC1
Tbio
Novelty:  0.00182088
Score:  0.56
Data Source:  STRINGDB
TTC16
Tdark
Novelty:  14.55737705
Score:  0.559
Data Source:  STRINGDB
ADGRA2
Tbio
Family:  GPCR
Novelty:  0.02854335
Score:  0.543
Data Source:  STRINGDB
GPR135
Tbio
Family:  GPCR
Novelty:  0.29123972
Score:  0.541
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
2
2
84.7
monocyte count
2
1
2
81.1
myeloid white cell count
1
1
1
73.9
leukocyte count
1
1
1
68.6
neutrophil count
2
1
2
59.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
84.7
monocyte count
2
81.1
myeloid white cell count
1
73.9
leukocyte count
1
68.6
neutrophil count
2
59.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
adhesion G protein-coupled receptor F1
VGNC:7883
462747
Mouse
MGI:1924846
77596
Dog
adhesion G protein-coupled receptor F1
VGNC:37638
474927
Horse
adhesion G protein-coupled receptor F1
VGNC:15103
100068434
Cow
adhesion G protein-coupled receptor F1
VGNC:25661
512637
Species
Name
OMA
EggNOG
Inparanoid
Chimp
adhesion G protein-coupled receptor F1
Mouse
Dog
adhesion G protein-coupled receptor F1
Horse
adhesion G protein-coupled receptor F1
Cow
adhesion G protein-coupled receptor F1
Publication Statistics
PubMed Score 14.37
PubMed score by year
PubTator Score 7.67
PubTator score by year
Patents
Patents by year
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Related Publications
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PMID
Year
Title