Tbio ADGRF1 Adhesion G-protein coupled receptor F1

Protein Summary

Description

Orphan receptor.

Uniprot Accession IDs

• Q5T601
• Q5KU15
• Q5T5Z9
• Q5T600
• Q86SM1
• Q8IXE3
• Q8IZF8
• Q96DQ1
• Q9H615

Gene Name

• ADGRF1

Ensembl ID

• ENST00000371243
• ENSP00000360289
• ENSG00000153292
• ENST00000371253
• ENSP00000360299

Symbol

• GPR110
• PGR19
• PGR19
• GPR110
• KPG_012
• hGPCR36

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.95
gene perturbation	0.75
microRNA	0.73
protein domain	0.73
cell type or tissue	0.7

Protein Classes

DTO Classes

Protein / G-protein Coupled Receptor / Adhesion Class / Adhesion G-protein Coupled Receptor F1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.87   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 176   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.87   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 176   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0