Tbio CCNJ Cyclin-J

Protein Classes

PANTHER Classes

Protein / Enzyme Modulator / Kinase Modulator / Kinase Activator / Cyclin-j

DTO Classes

Protein / Enzyme Modulator / Kinase Modulator / Kinase Activator / Cyclin-j

Protein Summary

Uniprot Accession IDs

• Q5T5M9
• B7Z4E7
• Q86XL1
• Q9NV69

Gene Name

• CCNJ

Ensembl ID

• ENST00000265992
• ENSP00000265992
• ENSG00000107443
• ENST00000403870
• ENSP00000384498
• ENST00000465148
• ENSP00000435373

Symbol

• bA690P14.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.71
virus perturbation	0.68
histone modification site profile	0.65
protein domain	0.58
transcription factor binding site profile	0.53

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.26   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 135   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.26   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 135   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Gene Ontology Terms (11)

Functions (2)

Components (3)

Processes (6)

Items per page:

10

1 – 2 of 2

GO Term	Evidence	Assigned by
cyclin-dependent protein serine/threonine kinase regulator activity	Inferred from Biological aspect of Ancestor (IBA)	GO_Central
protein kinase binding	Inferred from Biological aspect of Ancestor (IBA)	GO_Central

Protein-Protein Interactions (20)

Explore Interacting Targets

1 – 10 of 20

• See Interactions on String-DB

GORASP1

Tbio

Novelty: 0.0271696

p_int: 0.999940687

p_wrong: 0.000059312

Score: 0.158

Data Source: BioPlex,STRINGDB

POTEF

Tbio

Novelty: 0.01093698

p_int: 0.99834741

p_ni: 0.00165259

Score: 0.179

Data Source: BioPlex,STRINGDB

SPECC1L

Tbio

Novelty: 0.12603151

p_int: 0.794737781

p_ni: 0.205262219

Score: 0.187

Data Source: BioPlex,STRINGDB

MEGF9

Tdark

Novelty: 0.69250992

Score: 0.732

Data Source: STRINGDB

NAGA

Tbio

Family: Enzyme

Novelty: 0.00628096

Score: 0.682

Data Source: STRINGDB

FSHR

Tclin

Family: GPCR

Novelty: 0.00142021

Score: 0.636

Data Source: STRINGDB

CDO1

Tbio

Family: Enzyme

Novelty: 0.02161596

Score: 0.625

Data Source: STRINGDB

MKNK1

Tchem

Family: Kinase

Novelty: 0.01723237

Score: 0.575

Data Source: STRINGDB

GLA

Tclin

Family: Enzyme

Novelty: 0.0006641

Score: 0.526

Data Source: STRINGDB

ENPEP

Tchem

Family: Enzyme

Novelty: 0.00116769

Score: 0.513

Data Source: STRINGDB

Publication Statistics

PubMed Score  6.26

PubMed score by year

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PubTator Score  3.04

PubTator score by year

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Amino Acid Sequence

Residue Counts

Sequence

MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDL

1-70

FMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQW

70-140

NLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQVAAACVASSRIILRLSP

140-210

TWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYL

210-280

HQTHQTSLQYRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLS

280-350

VSYNRSYQINEHYPCITPCFER

350-372

MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINEHYPCITPCFER

Find similar targets by:

Uniprot Keyword

Alternative splicing
Complete proteome
Cyclin
Reference proteome