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Tdark
TMEM273
Transmembrane protein 273

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374148
  • ENSP00000363263
  • ENSG00000204161
  • ENST00000374153
  • ENSP00000363268
  • ENST00000474718
  • ENSP00000417246

Symbol
  • C10orf128
  • C10orf128
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.06   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 6   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.06   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 6   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
1
1
82.6
mean corpuscular volume
1
1
1
79.3
myeloid white cell count
1
1
1
78.1
monocyte count
1
1
1
76.5
platelet crit
1
1
1
71.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
82.6
mean corpuscular volume
1
79.3
myeloid white cell count
1
78.1
monocyte count
1
76.5
platelet crit
1
71.5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5T292-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (20)
1 – 10 of 20
TNRC6C
Tbio
Novelty:  0.09764186
Score:  0.641
Data Source:  STRINGDB
RPUSD1
Tdark
Family:  Enzyme
Novelty:  2.14978301
Score:  0.586
Data Source:  STRINGDB
TMEM163
Tbio
Novelty:  0.04613489
Score:  0.582
Data Source:  STRINGDB
WDR86
Tdark
Novelty:  3.47953216
Score:  0.582
Data Source:  STRINGDB
FAM92A
Tbio
Novelty:  0.11312783
Score:  0.541
Data Source:  STRINGDB
VSTM4
Tdark
Novelty:  0.46711608
Score:  0.526
Data Source:  STRINGDB
RBM46
Tbio
Novelty:  0.10180853
Score:  0.517
Data Source:  STRINGDB
KATNBL1
Tdark
Novelty:  1.43589506
Score:  0.509
Data Source:  STRINGDB
ITPRIP
Tdark
Novelty:  0.27051709
Score:  0.503
Data Source:  STRINGDB
NOVA1
Tbio
Novelty:  0.01298544
Score:  0.492
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.06

PubMed score by year
PubTator Score  0.05

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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