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Tbio
DDX59
Probable ATP-dependent RNA helicase DDX59

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000331314
  • ENSP00000330460
  • ENSG00000118197
  • ENST00000447706
  • ENSP00000394367

Symbol
  • ZNHIT5
  • OFD5
  • ZNHIT5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.95
histone modification site profile
0.91
transcription factor binding site profile
0.87
protein domain
0.85
kinase perturbation
0.76


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.52   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 200   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.52   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 200   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DEAD-box helicase 59
VGNC:10596
737453
Macaque
DEAD-box helicase 59
709192
Mouse
MGI:1915247
67997
Rat
RGD:1359520
289402
Dog
DEAD-box helicase 59
VGNC:39868
480006
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DEAD-box helicase 59
Macaque
DEAD-box helicase 59
Mouse
Rat
Dog
DEAD-box helicase 59
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q5T1V6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (7)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (134)
1 – 10 of 134
LINGO3
Tdark
Novelty: 0.64657784
Score: 0.783
Data Source: STRINGDB
DHX37
Tdark
Family: Enzyme
Novelty: 0.02474351
Score: 0.74
Data Source: STRINGDB
TMEM231
Tbio
Novelty: 0.17100188
Score: 0.71
Data Source: STRINGDB
CPLANE1
Tbio
Novelty: 0.0245689
Score: 0.686
Data Source: STRINGDB
TMEM216
Tbio
Novelty: 0.07870718
Score: 0.683
Data Source: STRINGDB
ZNHIT6
Tbio
Novelty: 1.1021845
Score: 0.678
Data Source: STRINGDB
NOP56
Tbio
Novelty: 0.01256937
Score: 0.675
Data Source: STRINGDB
DHX32
Tbio
Family: Enzyme
Novelty: 0.09993874
Score: 0.665
Data Source: STRINGDB
ZNHIT1
Tbio
Novelty: 0.00390514
Score: 0.661
Data Source: STRINGDB
DDX24
Tbio
Family: Enzyme
Novelty: 0.17803446
Score: 0.651
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.52

PubMed score by year
PubTator Score  1.75

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer