Tbio FRMPD1 FERM and PDZ domain-containing protein 1

Protein Summary

Description

Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.

Uniprot Accession IDs

• Q5SYB0
• B4DZC8
• B7Z807
• D3DRQ3
• Q14C73
• Q5HY96
• Q9Y2H3

Gene Name

• FRMPD1

Ensembl ID

• ENST00000377765
• ENSP00000366995
• ENSG00000070601
• ENST00000539465
• ENSP00000444411

Symbol

• FRMD2
• KIAA0967
• FRMD2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.85
histone modification site profile	0.82
trait	0.75
small molecule perturbation	0.63
cell type or tissue	0.57

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.46   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 99   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.46   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 99   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0