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Tbio
LY6G6F
Lymphocyte antigen 6 complex locus protein G6f

Protein Summary
Description
May play a role in the downstream signal transduction pathways involving GRB2 and GRB7. The human G6f protein is a type I transmembrane protein belonging to the immunoglobin (Ig) superfamily, which is comprised of cell-surface proteins involved in the immune system and cellular recognition (de Vet et al., 2003 [PubMed 12852788]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375832
  • ENSP00000364992
  • ENSG00000204424
  • ENST00000383420
  • ENSP00000372912
  • ENSG00000243804
  • ENST00000442105
  • ENSP00000404621
  • ENSG00000241822
  • ENST00000446062
  • ENSP00000404884
  • ENSG00000239741
  • ENST00000447811
  • ENSP00000409959
  • ENSG00000240008
  • ENST00000453044
  • ENSP00000389102
  • ENSG00000240957
  • ENST00000455632
  • ENSP00000407535
  • ENSG00000243003

Symbol
  • C6orf21
  • G6F
  • LY6G6D
  • NG32
  • G6f
  • NG32
  • LY6G6
  • LY6G6D
  • C6orf21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
tissue
0.58
disease
0.57
phenotype
0.51
cell line
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.08   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 134   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.08   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
GRB7
Tchem
Novelty:  0.0091833
Score:  0.815
Data Source:  STRINGDB
LY6G5B
Tdark
Novelty:  0.07346971
Score:  0.686
Data Source:  STRINGDB
MPIG6B
Tbio
Novelty:  0.04808462
Score:  0.67
Data Source:  STRINGDB
GRB2
Tchem
Novelty:  0.00091605
Score:  0.608
Data Source:  STRINGDB
SMIM29
Tbio
Novelty:  0.79562094
Score:  0.574
Data Source:  STRINGDB
LY6G5C
Tdark
Novelty:  0.1353418
Score:  0.559
Data Source:  STRINGDB
LY6G6C
Tbio
Novelty:  0.07576412
Score:  0.521
Data Source:  STRINGDB
PRR3
Tdark
Novelty:  0.71308048
Score:  0.52
Data Source:  STRINGDB
LY6L
Tdark
Novelty:  14.46115589
Score:  0.513
Data Source:  STRINGDB
GP9
Tbio
Novelty:  0.00365769
Score:  0.512
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Hemostasis (R-HSA-109582)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Hemostasis
Reactome
Platelet activation, signaling and aggregation
Reactome
Platelet degranulation
Reactome
Response to elevated platelet cytosolic Ca2+
Name
Explore in Pharos
Explore in Source
Hemostasis
Platelet activation, signaling and aggregation
Platelet degranulation
Response to elevated platelet cytosolic Ca2+
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (455)
Items per page:
1 – 5 of 455
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
3
0
3
96.3
1
3
0
3
96.3
1
3
0
3
96.3
1
3
0
3
96.3
1
3
0
3
96.3
Items per page:
1 – 5 of 455
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
3
96.3
0
3
96.3
0
3
96.3
0
3
96.3
0
3
96.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3616082
433099
Rat
RGD:1303333
309609
Cow
lymphocyte antigen 6 family member G6F
539920
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Cow
lymphocyte antigen 6 family member G6F
Publication Statistics
PubMed Score 9.08
PubMed score by year
PubTator Score 2.12
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title