Tbio CALHM6 Calcium homeostasis modulator protein 6

Protein Summary

Description

Pore-forming subunit of a voltage-gated ion channel.

Uniprot Accession IDs

• Q5R3K3
• B9EJB0
• Q5R3K4

Gene Name

• CALHM6

Ensembl ID

• ENST00000368605
• ENSP00000357594
• ENSG00000188820
• ENST00000368606
• ENSP00000357595

Symbol

• C6orf187
• FAM26F
• INAM
• FAM26F
• C6orf187
• dJ93H18.5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

DTO Classes

Protein / Ion Channel / Fam26 Family / Protein Fam26f

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.9   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 34   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.9   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0