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Tbio
RTP2
Receptor-transporting protein 2

Protein Summary
Description
Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358241
  • ENSP00000350976
  • ENSG00000198471

Symbol
  • Z3CXXC2
  • Z3CXXC2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.82
tissue sample
0.63
cell line
0.61
tissue
0.41
disease
0.3


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.99   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.99   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (418)
TMEM159
Tdark
Novelty:  0.22237677
p_int:  0.995465318
p_ni:  0.000081052
p_wrong:  0.00445363
Data Source:  BioPlex
PIGU
Tbio
Novelty:  0.11800036
p_int:  0.975305288
p_ni:  0.024694645
p_wrong:  6.7e-8
Data Source:  BioPlex
SLC7A2
Tbio
Family:  Transporter
Novelty:  0.02262224
p_int:  0.951831723
p_ni:  0.047530822
p_wrong:  0.000637454
Data Source:  BioPlex
ATP12A
Tchem
Family:  Transporter
Novelty:  0.00008793
p_int:  0.951059884
p_ni:  0.048940114
p_wrong:  1e-9
Data Source:  BioPlex
TMEM192
Tbio
Novelty:  0.30699087
p_int:  0.923379212
p_ni:  0.071684732
p_wrong:  0.004936056
Data Source:  BioPlex
FAM118B
Tdark
Novelty:  0.48168976
p_int:  0.91292593
p_ni:  0.054293635
p_wrong:  0.032780435
Data Source:  BioPlex
REEP5
Tbio
Novelty:  0.00160455
p_int:  0.883881785
p_ni:  0.115948071
p_wrong:  0.000170144
Score:  0.169
Data Source:  BioPlex,STRINGDB
APOB
Tchem
Novelty:  0.00008247
p_int:  0.875653065
p_ni:  0.123511313
p_wrong:  0.000835622
Data Source:  BioPlex
FNTB
Tclin
Family:  Enzyme
Novelty:  0.07434994
p_int:  0.820227512
p_ni:  0.174733159
p_wrong:  0.005039329
Data Source:  BioPlex
GPAA1
Tbio
Novelty:  0.01874575
p_int:  0.77419743
p_ni:  0.22580257
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
G alpha (s) signalling events (R-HSA-418555)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (s) signalling events
Reactome
GPCR downstream signalling
Reactome
Olfactory Signaling Pathway
Reactome
Signal Transduction
Reactome
Signaling by GPCR
Name
Explore in Pharos
Explore in Source
G alpha (s) signalling events
GPCR downstream signalling
Olfactory Signaling Pathway
Signal Transduction
Signaling by GPCR
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil percentage of leukocytes
2
2
2
79.3
body height
1
1
1
66
basophil count
2
2
2
65.9
monocyte percentage of leukocytes
1
1
1
64
basophil percentage of granulocytes
1
1
1
53.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil percentage of leukocytes
2
79.3
body height
1
66
basophil count
2
65.9
monocyte percentage of leukocytes
1
64
basophil percentage of granulocytes
1
53.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
receptor transporter protein 2
VGNC:10341
471036
Mouse
MGI:2685451
224055
Rat
RGD:1565722
303835
Horse
receptor transporter protein 2
VGNC:22620
100068300
Cow
receptor transporter protein 2
VGNC:34210
539817
Species
Name
OMA
EggNOG
Inparanoid
Chimp
receptor transporter protein 2
Mouse
Rat
Horse
receptor transporter protein 2
Cow
receptor transporter protein 2
Publication Statistics
PubMed Score 15.99
PubMed score by year
PubTator Score 5.12
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title