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Tdark
SPDYC
Speedy protein C

Protein Summary
Description
Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377185
  • ENSP00000366390
  • ENSG00000204710

Symbol
  • RINGOC
  • Ringo2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.63
cell line
0.52
tissue
0.42
chemical
0.41
protein complex
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.06   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.06   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0