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Tdark
FAM78A
Protein FAM78A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372271
  • ENSP00000361345
  • ENSG00000126882

Symbol
  • C9orf59
  • C9orf59
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor
0.67
transcription factor binding site profile
0.64
microRNA
0.6
PubMedID
0.6
cell type or tissue
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.05   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 108   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.05   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 108   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (26)
1 – 10 of 26
ADD3
Tbio
Family:  Enzyme
Novelty:  0.02164464
p_int:  0.978760116
p_ni:  0.021239883
p_wrong:  1e-9
Score:  0.359
Data Source:  BioPlex,STRINGDB
ZNF540
Tbio
Family:  TF
Novelty:  0.42941109
Score:  0.67
Data Source:  STRINGDB
PCDHAC1
Tdark
Novelty:  0.3734734
Score:  0.669
Data Source:  STRINGDB
RIMS4
Tbio
Novelty:  0.12325795
Score:  0.655
Data Source:  STRINGDB
ZNF671
Tbio
Family:  TF
Novelty:  0.21222678
Score:  0.648
Data Source:  STRINGDB
AP2A1
Tbio
Novelty:  0.08554974
Score:  0.637
Data Source:  STRINGDB
ALKAL1
Tbio
Novelty:  0.12828794
Score:  0.591
Data Source:  STRINGDB
ZNF154
Tbio
Family:  TF
Novelty:  0.1287115
Score:  0.571
Data Source:  STRINGDB
PRAC1
Tbio
Novelty:  0.03902014
Score:  0.557
Data Source:  STRINGDB
KHDRBS2
Tbio
Novelty:  0.01986638
Score:  0.539
Data Source:  STRINGDB
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
1
1
5
55.2
urate measurement
1
1
1
7.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
5
55.2
urate measurement
1
7.9
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
family with sequence similarity 78 member A
715560
Mouse
MGI:2443569
241303
Rat
RGD:1566351
499776
Dog
family with sequence similarity 78 member A
VGNC:40695
480692
Horse
family with sequence similarity 78 member A
VGNC:17885
100066755
Species
Name
OMA
EggNOG
Inparanoid
Macaque
family with sequence similarity 78 member A
Mouse
Rat
Dog
family with sequence similarity 78 member A
Horse
family with sequence similarity 78 member A
Publication Statistics
PubMed Score 1.05
PubMed score by year
PubTator Score 0.21
PubTator score by year