Tdark PSMG4 Proteasome assembly chaperone 4

Protein Summary

Description

Chaperone protein which promotes assembly of the 20S proteasome.

Uniprot Accession IDs

• Q5JS54
• C9J2F8
• F8WBZ2
• Q5JS53
• Q5JS56
• PAC-4

Gene Name

• PSMG4

Ensembl ID

• ENST00000419065
• ENSP00000392353
• ENSG00000180822
• ENST00000438998
• ENSP00000413353
• ENST00000473000
• ENSP00000418241

Symbol

• C6orf86
• PAC4
• PAC4
• C6orf86
• bA506K6.2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.66
tissue sample	0.64
transcription factor binding site profile	0.59
gene perturbation	0.56
transcription factor	0.52

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.49   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 4   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.49   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0