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Tbio
MTUS2
Microtubule-associated tumor suppressor candidate 2

Protein Summary
Description
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380808
  • ENSP00000370186
  • ENSG00000132938
  • ENST00000542829
  • ENSP00000445403

Symbol
  • CAZIP
  • KIAA0774
  • TIP150
  • ICIS
  • CAZIP
  • TIP150
  • KIAA0774
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
cell type or tissue
0.74
phenotype
0.68
tissue sample
0.68
transcription factor
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 197.19   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 197.19   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Protein-Protein Interactions (51)
1 – 10 of 51
MTUS1
Tbio
Novelty: 0.00309687
p_int: 0.999992111
p_ni: 0.000007887
p_wrong: 1e-9
Score: 0.199
Data Source: BioPlex,STRINGDB
CCDC6
Tbio
Novelty: 0.01216915
p_int: 0.999786157
p_ni: 0.000213843
Data Source: BioPlex
ATP11C
Tbio
Family: Transporter
Novelty: 0.06715014
p_int: 0.998488127
p_ni: 0.001511873
Data Source: BioPlex
MYADM
Tbio
Novelty: 0.09214874
p_int: 0.996094178
p_ni: 0.00390581
p_wrong: 1.2e-8
Data Source: BioPlex
TMEM63B
Tdark
Family: IC
Novelty: 0.63157895
p_int: 0.994571762
p_ni: 0.005428234
p_wrong: 4e-9
Score: 0.159
Data Source: BioPlex,STRINGDB
ATP6V0C
Tbio
Family: Enzyme
Novelty: 0.01276499
p_int: 0.99245456
p_ni: 0.007545358
p_wrong: 8.1e-8
Score: 0.205
Data Source: BioPlex,STRINGDB
ATP6V0A2
Tbio
Family: Enzyme
Novelty: 0.0033925
p_int: 0.99216118
p_ni: 0.007838817
p_wrong: 4e-9
Score: 0.219
Data Source: BioPlex,STRINGDB
DCAF10
Tdark
Novelty: 10
p_int: 0.984352257
p_ni: 0.015647743
Data Source: BioPlex
AFDN
Tbio
Novelty: 0.00626505
p_int: 0.983553626
p_ni: 0.016446366
p_wrong: 8e-9
Data Source: BioPlex
RABL6
Tbio
Family: Enzyme
Novelty: 0.1308615
p_int: 0.981551557
p_ni: 0.018440206
p_wrong: 0.000008237
Data Source: BioPlex
Publication Statistics
PubMed Score  197.19

PubMed score by year
PubTator Score  3.38

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer