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Tdark
C3orf38
Uncharacterized protein C3orf38

Protein Summary
Description
May be involved in apoptosis regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318887
  • ENSP00000322469
  • ENSG00000179021
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (24)
1 – 10 of 24
BAG4
Tbio
Novelty:  0.02660607
p_int:  0.999986261
p_ni:  0.000013507
p_wrong:  2.31e-7
Score:  0.219
Data Source:  BioPlex,STRINGDB
DNAJB4
Tbio
Novelty:  0.03467352
p_int:  0.999713446
p_ni:  0.000286546
p_wrong:  8e-9
Score:  0.527
Data Source:  BioPlex,STRINGDB
TCEAL5
Tdark
Novelty:  1.78893063
p_int:  0.999459121
p_ni:  0.000014325
p_wrong:  0.000526553
Data Source:  BioPlex
TMEM87A
Tdark
Novelty:  0.33614983
p_int:  0.796070235
p_ni:  0.001051153
p_wrong:  0.202878612
Data Source:  BioPlex
ZNF654
Tdark
Novelty:  2.8241123
Score:  0.942
Data Source:  STRINGDB
NUBP2
Tbio
Novelty:  0.01136095
Score:  0.664
Data Source:  STRINGDB
CGGBP1
Tbio
Novelty:  0.10880271
Score:  0.644
Data Source:  STRINGDB
HTR1A
Tclin
Family:  GPCR
Novelty:  0.00015658
Score:  0.626
Data Source:  STRINGDB
SIX6OS1
Tdark
Novelty:  0.49801014
Score:  0.588
Data Source:  STRINGDB
NPM3
Tbio
Novelty:  0.11783423
Score:  0.565
Data Source:  STRINGDB
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
3
3
83.3
mean corpuscular hemoglobin concentration
1
1
1
77
comparative body size at age 10, self-reported
1
1
1
63.4
red blood cell density measurement
1
1
1
60.5
smoking status measurement
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
83.3
mean corpuscular hemoglobin concentration
1
77
comparative body size at age 10, self-reported
1
63.4
red blood cell density measurement
1
60.5
smoking status measurement
1
35
Find similar targets by:
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 3 C3orf38 homolog
VGNC:5033
460530
Macaque
chromosome 2 open reading frame, human C3orf38
693668
Mouse
MGI:1914859
67609
Dog
chromosome 33 C3orf38 homolog
VGNC:52558
606769
Horse
chromosome 3 open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:28384]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 3 C3orf38 homolog
Macaque
chromosome 2 open reading frame, human C3orf38
Mouse
Dog
chromosome 33 C3orf38 homolog
Horse
chromosome 3 open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:28384]
Publication Statistics
PubMed Score 0.51
PubMed score by year
PubTator Score 0.08
PubTator score by year