Tbio EMC4 ER membrane protein complex subunit 4

Protein Summary

Description

May mediate anti-apoptotic activity.

Uniprot Accession IDs

• Q5J8M3
• A8K3A9
• B4DJQ4
• Q96KX9
• Q9BUI5
• Q9P0T9

Gene Name

• EMC4

Ensembl ID

• ENST00000249209
• ENSP00000249209
• ENSG00000128463
• ENST00000267750
• ENSP00000267750

Symbol

• TMEM85
• PIG17
• TMEM85

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.98
histone modification site profile	0.92
virus perturbation	0.85
ligand (protein) perturbation	0.83
transcription factor binding site profile	0.69

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.57   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 63   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.57   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0