Tdark C6orf226 Uncharacterized protein C6orf226

Protein Summary

Uniprot Accession IDs

• Q5I0X4

Gene Name

• C6orf226

Ensembl ID

• ENST00000408925
• ENSP00000386146
• ENSG00000221821

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 6   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.16   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 6   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

tutorial

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Find Targets by Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (3)

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

Go To Tool

ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

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Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (9)

Explore Interacting Targets

1 – 9 of 9

• See Interactions on String-DB

ACAA1

Tbio

Family:  Enzyme

Novelty:  0.00710465

p_int:  0.999999999

p_ni:  1e-9

Score:  0.859

Data Source:  BioPlex,STRINGDB

PEX7

Tbio

Novelty:  0.01487923

p_int:  0.999999997

p_wrong:  3e-9

Score:  0.799

Data Source:  BioPlex,STRINGDB

PHYH

Tbio

Family:  Enzyme

Novelty:  0.00277669

p_int:  0.999999876

p_ni:  1.24e-7

Score:  0.68

Data Source:  BioPlex,STRINGDB

CHRNA4

Tclin

Family:  IC

Novelty:  0.00494934

Score:  0.658

Data Source:  STRINGDB

PAQR5

Tbio

Novelty:  0.05821975

Score:  0.557

Data Source:  STRINGDB

HIST1H2BM

Tdark

Novelty:  0.70393417

Score:  0.53

Data Source:  STRINGDB

CCDC9B

Tdark

Novelty:  1.38180738

Score:  0.479

Data Source:  STRINGDB

CCDC9

Tdark

Novelty:  0.73149492

Score:  0.476

Data Source:  STRINGDB

CDHR1

Tbio

Novelty:  0.03000456

Score:  0.447

Data Source:  STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (0)

No GO Terms found

Disease Associations (null)

No disease associations found

GWAS Traits (9)

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 5 of 9

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
apolipoprotein A 1 measurement	EFO_0004614	2	3	3		92.7
apolipoprotein B measurement	EFO_0004615	2	3	3		86.8
high density lipoprotein cholesterol measurement	EFO_0004612	3	3	4		83.6
bilirubin measurement	EFO_0004570	1	1	1		67.3
homocysteine measurement	EFO_0004578	1	1	1		47.7

• Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

5

1 – 5 of 9

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)	Provenance
apolipoprotein A 1 measurement	EFO_0004614	3		92.7
apolipoprotein B measurement	EFO_0004615	3		86.8
high density lipoprotein cholesterol measurement	EFO_0004612	4		83.6
bilirubin measurement	EFO_0004570	1		67.3
homocysteine measurement	EFO_0004578	1		47.7

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Find similar targets by:

UniProt Keyword Find Similar Targets

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GWAS Trait Find Similar Targets

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apolipoprotein A 1 measurement
apolipoprotein B measurement
bilirubin measurement
hematocrit
high density lipoprotein cholesterol measurement
homocysteine measurement
low density lipoprotein cholesterol measurement
mean platelet volume
smoking status measurement

IDG Resources

No IDG generated resources found

Orthologs (3)

1 – 3 of 3

Species	Name	Source ID	Gene ID	OMA	EggNOG	Inparanoid
Chimp	chromosome unknown open reading frame, human C6orf226		739407
Mouse	RIKEN cDNA 2310039H08 gene	MGI:1914351	67101
Rat	hypothetical protein LOC681367	RGD:1596723	681367

Species	Name	OMA	EggNOG	Inparanoid
Chimp	chromosome unknown open reading frame, human C6orf226
Mouse	RIKEN cDNA 2310039H08 gene
Rat	hypothetical protein LOC681367

Publication Statistics

PubMed Score 0.16

PubMed score by year

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Related Publications

Text Mined References (2)

Items per page:

10

0 of 0

PMID	Year	Title