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Tbio
TAF7L
Transcription initiation factor TFIID subunit 7-like

Protein Summary
Description
Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity). This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324762
  • ENSP00000320283
  • ENSG00000102387
  • ENST00000356784
  • ENSP00000349235
  • ENST00000372907
  • ENSP00000361998

Symbol
  • TAF2Q
  • CT40
  • TAF2Q
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
cell type or tissue
0.63
molecular function
0.6
cellular component
0.5
tissue sample
0.5


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.21   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 105   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.21   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (100)
TAF1
Tchem
Family:  Kinase
Novelty:  0.00555929
p_int:  0.999999999
p_ni:  1e-9
Score:  0.997
Data Source:  BioPlex,STRINGDB
TAF3
Tbio
Family:  Epigenetic
Novelty:  0.05517331
p_int:  0.999999996
p_ni:  1e-9
p_wrong:  3e-9
Score:  0.995
Data Source:  BioPlex,STRINGDB
TAF9B
Tbio
Novelty:  0.0285313
p_int:  0.999999911
p_ni:  8.9e-8
Score:  0.988
Data Source:  BioPlex,STRINGDB
TAF2
Tbio
Novelty:  0.0397428
p_int:  0.999999882
p_ni:  1.03e-7
p_wrong:  1.5e-8
Score:  0.994
Data Source:  BioPlex,STRINGDB
TAF11
Tchem
Novelty:  0.10299251
p_int:  0.999999832
p_ni:  3e-9
p_wrong:  1.65e-7
Score:  0.994
Data Source:  BioPlex,STRINGDB
TAF6
Tbio
Novelty:  0.04357176
p_int:  0.999999678
p_ni:  3.18e-7
p_wrong:  3e-9
Score:  0.998
Data Source:  BioPlex,STRINGDB
TAF5
Tbio
Novelty:  0.05443551
p_int:  0.999999409
p_ni:  5.91e-7
Score:  0.991
Data Source:  BioPlex,STRINGDB
TAF4B
Tbio
Novelty:  0.70515005
p_int:  0.999999121
p_ni:  8.07e-7
p_wrong:  7.2e-8
Score:  0.994
Data Source:  BioPlex,STRINGDB
AK6
Tbio
Family:  Kinase
Novelty:  0.173427
p_int:  0.999998282
p_ni:  0.000001717
Score:  0.782
Data Source:  BioPlex,STRINGDB
TAF8
Tbio
Novelty:  0.01056638
p_int:  0.999997705
p_ni:  0.000002295
Score:  0.99
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (20)
Disease (R-HSA-1643685)

Click on a row in the table to change the structure displayed.

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Items per page:
1 – 5 of 19
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Disease
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
HIV Infection
Reactome
HIV Life Cycle
Name
Explore in Pharos
Explore in Source
Disease
Gene expression (Transcription)
Generic Transcription Pathway
HIV Infection
HIV Life Cycle
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
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Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
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IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
TATA-box binding protein associated factor 7 like
VGNC:11627
739276
Macaque
TATA-box binding protein associated factor 7 like
702772
Mouse
MGI:3588269
619332
Rat
RGD:1564898
363493
Dog
TATA-box binding protein associated factor 7 like
VGNC:47088
480985
Species
Name
OMA
EggNOG
Inparanoid
Chimp
TATA-box binding protein associated factor 7 like
Macaque
TATA-box binding protein associated factor 7 like
Mouse
Rat
Dog
TATA-box binding protein associated factor 7 like
Publication Statistics
PubMed Score 14.21
PubMed score by year
PubTator Score 12.64
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title