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Tdark
TCEAL5
Transcription elongation factor A protein-like 5

Protein Classes
Protein Summary
Description
May be involved in transcriptional regulation. This gene, which is located on the X chromosome, encodes a protein which contains a BEX (brain expressed X-liked like family) domain. This domain is found in proteins encoded by the TCEAL elongation factor (transcription elongation factor A (SII)-like) gene family also located on the X chromosome. The coding region for this gene is located entirely in the terminal exon. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372680
  • ENSP00000361765
  • ENSG00000204065

Symbol
  • WEX4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.62
tissue sample
0.62
virus perturbation
0.55
tissue
0.49
PubMedID
0.47


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
1
1
1
3.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
1
3.9
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transcription elongation factor A like 5
695800
Mouse
MGI:3036236
331532
Dog
transcription elongation factor A protein-like 5
100686274
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transcription elongation factor A like 5
Mouse
Dog
transcription elongation factor A protein-like 5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5H9L2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (29)
1 – 10 of 29
TCEAL3
Tdark
Novelty:  1.59394782
p_int:  0.999999998
p_wrong:  2e-9
Data Source:  BioPlex
C3orf38
Tdark
Novelty:  2.10467478
p_int:  0.999459121
p_ni:  0.000014325
p_wrong:  0.000526553
Data Source:  BioPlex
KLHL8
Tdark
Novelty:  0.4838314
p_int:  0.998882039
p_ni:  0.001116728
p_wrong:  0.000001233
Data Source:  BioPlex
ZNF74
Tbio
Family:  TF
Novelty:  0.10554307
p_int:  0.995493456
p_ni:  0.000157776
p_wrong:  0.004348768
Data Source:  BioPlex
USP7
Tchem
Family:  Enzyme
Novelty:  0.00412878
p_int:  0.928911815
p_ni:  0.071088185
Data Source:  BioPlex
BEX5
Tdark
Novelty:  0.2964824
Score:  0.749
Data Source:  STRINGDB
TCEAL8
Tdark
Novelty:  1.0765394
Score:  0.718
Data Source:  STRINGDB
BEX1
Tbio
Novelty:  0.03230695
Score:  0.695
Data Source:  STRINGDB
BEX3
Tbio
Novelty:  0.02578005
Score:  0.657
Data Source:  STRINGDB
RAB40A
Tbio
Novelty:  0.12112671
Score:  0.599
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.69

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer