Tbio NMS Neuromedin-S

Protein Summary

Description

Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. This gene encodes a member of the neuromedin family of neuropeptides. The encoded preproprotein is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. [provided by RefSeq, May 2016]

Uniprot Accession IDs

• Q5H8A3

Gene Name

• NMS

Ensembl ID

• ENST00000376865
• ENSP00000366061
• ENSG00000204640

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.52
transcription factor	0.43
tissue	0.42
cellular component	0.4
disease	0.37

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.38   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 107   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.38   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0