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Tdark
FSIP2
Fibrous sheath-interacting protein 2

Protein Summary
Description
This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000424728
  • ENSP00000401306
  • ENSG00000188738

Symbol
  • SPGF34
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.69
cell line
0.6
cellular component
0.52
histone modification site profile
0.46
virus perturbation
0.45


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2664111
241516
Dog
fibrous sheath interacting protein 2
VGNC:53095
611005
Cow
fibrous sheath interacting protein 2
100140733
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
fibrous sheath interacting protein 2
Cow
fibrous sheath interacting protein 2
Protein Structure (0 Structures, 29 AlphaFold Models)
RepresentationColor Scheme

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (26)
1 – 10 of 26
FSIP1
Tbio
Novelty: 0.02610106
Score: 0.81
Data Source: STRINGDB
AKAP4
Tbio
Family: Enzyme
Novelty: 0.00760557
Score: 0.803
Data Source: STRINGDB
ABCC12
Tbio
Family: Transporter
Novelty: 0.06927244
Score: 0.71
Data Source: STRINGDB
CMBL
Tbio
Family: Enzyme
Novelty: 0.00579339
Score: 0.706
Data Source: STRINGDB
SPATS2
Tdark
Novelty: 0.20594325
Score: 0.696
Data Source: STRINGDB
AKAP3
Tbio
Family: Enzyme
Novelty: 0.030936
Score: 0.663
Data Source: STRINGDB
TMED2
Tbio
Novelty: 0.03731104
Score: 0.643
Data Source: STRINGDB
ABCC11
Tbio
Family: Transporter
Novelty: 0.01382192
Score: 0.529
Data Source: STRINGDB
POTEI
Tdark
Novelty: 0.41311202
Score: 0.514
Data Source: STRINGDB
NPY2R
Tchem
Family: GPCR
Novelty: 0.01177255
Score: 0.507
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.06

PubMed score by year
PubTator Score  2.32

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer