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Tbio
ZNF385B
Zinc finger protein 385B

Protein Summary
Description
May play a role in p53/TP53-mediated apoptosis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336917
  • ENSP00000338225
  • ENSG00000144331
  • ENST00000409343
  • ENSP00000386379
  • ENST00000409692
  • ENSP00000386507
  • ENST00000644742
  • ENSP00000494328

Symbol
  • ZNF533
  • ZNF533
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.99
virus perturbation
0.92
transcription factor
0.67
histone modification site profile
0.66
cell type or tissue
0.62


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.5   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 198   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.5   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 198   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
2
3
96.9
sex hormone-binding globulin measurement
2
1
2
61.2
sudden cardiac arrest
1
1
0
1.7
56.5
intelligence
1
1
0
5.5
55.2
pulse pressure measurement
1
1
1
5.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
3
96.9
sex hormone-binding globulin measurement
2
61.2
sudden cardiac arrest
0
1.7
56.5
intelligence
0
5.5
55.2
pulse pressure measurement
1
5.8
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 385B
VGNC:3884
459788
Macaque
zinc finger protein 385B
704204
Mouse
MGI:2444734
241494
Rat
RGD:1311181
311137
Dog
zinc finger protein 385B
VGNC:48715
488426
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 385B
Macaque
zinc finger protein 385B
Mouse
Rat
Dog
zinc finger protein 385B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q569K4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (6)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (37)
1 – 10 of 37
ZNF674
Tdark
Family: TF
Novelty: 0.29358331
Score: 0.806
Data Source: STRINGDB
ZNF81
Tbio
Family: TF
Novelty: 0.19441315
Score: 0.803
Data Source: STRINGDB
ZNF41
Tbio
Family: TF
Novelty: 0.1617438
Score: 0.8
Data Source: STRINGDB
MRPL33
Tdark
Novelty: 0.49802524
Score: 0.722
Data Source: STRINGDB
PLCXD3
Tdark
Novelty: 0.2326972
Score: 0.671
Data Source: STRINGDB
PARD3B
Tbio
Novelty: 0.09155541
Score: 0.629
Data Source: STRINGDB
LRRC3
Tdark
Novelty: 0.13484671
Score: 0.544
Data Source: STRINGDB
HPSE
Tchem
Family: Enzyme
Novelty: 0.00162921
Score: 0.537
Data Source: STRINGDB
C9orf152
Tdark
Novelty: 2.9794893
Score: 0.497
Data Source: STRINGDB
RCAN2
Tbio
Novelty: 0.00174006
Score: 0.487
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.50

PubMed score by year
PubTator Score  5.43

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer