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Tchem
SBK1
Serine/threonine-protein kinase SBK1

Protein Summary
Description
May be involved in signal-transduction pathways related to the control of brain development.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341901
  • ENSP00000343248
  • ENSG00000188322

Symbol
  • SBK
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
protein domain
0.73
histone modification site profile
0.69
transcription factor binding site profile
0.57
PubMedID
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.52   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 20   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.52   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intelligence
3
7
4
6.2
96.1
body mass index
5
1
7
89.2
waist circumference
1
1
1
44.7
tonsillectomy risk measurement
1
1
0
1.1
34.3
mathematical ability
1
1
1
26.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intelligence
4
6.2
96.1
body mass index
7
89.2
waist circumference
1
44.7
tonsillectomy risk measurement
0
1.1
34.3
mathematical ability
1
26.9
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (24)
1 – 10 of 24
STYK1
Tbio
Family: Kinase
Novelty: 0.01337491
Score: 0.647
Data Source: STRINGDB
INVS
Tbio
Novelty: 0.00834489
Score: 0.625
Data Source: STRINGDB
GNPTG
Tbio
Family: Enzyme
Novelty: 0.03345886
Score: 0.615
Data Source: STRINGDB
RHOT2
Tbio
Family: Enzyme
Novelty: 0.01712732
Score: 0.561
Data Source: STRINGDB
NLRC3
Tbio
Novelty: 0.0205634
Score: 0.527
Data Source: STRINGDB
PHF21B
Tbio
Family: Epigenetic
Novelty: 0.17016704
Score: 0.501
Data Source: STRINGDB
IRGQ
Tdark
Family: Enzyme
Novelty: 0.9065415
Score: 0.483
Data Source: STRINGDB
APOBR
Tbio
Novelty: 0.06449114
Score: 0.483
Data Source: STRINGDB
TMEM201
Tbio
Novelty: 0.00616362
Score: 0.478
Data Source: STRINGDB
TTC9B
Tdark
Novelty: 0.25942345
Score: 0.478
Data Source: STRINGDB
Publication Statistics
PubMed Score  18.52

PubMed score by year
PubTator Score  4.87

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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