Protein Summary
Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation (PubMed:28040436). Promotes colorectal cancer cell malignancy (PubMed:28040436).
- ENST00000397609
- ENSP00000380734
- ENSG00000171262
- ENST00000491535
- ENSP00000453166
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 0.91 | ||
transcription factor perturbation | 0.84 | ||
transcription factor binding site profile | 0.77 | ||
tissue sample | 0.63 | ||
histone modification site profile | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.17 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 99 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.17 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 99 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (41)
DDX1
Family: Enzyme
Novelty: 0.01691884
p_int: 0.999643472
p_ni: 0.000356528
Score: 0.999
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (3)
Reactome (3)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | tRNA processing | ||||
Reactome | tRNA processing in the nucleus | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Metabolism of RNA | ||||
tRNA processing | ||||
tRNA processing in the nucleus | ||||
Viral Interactions (0)
Gene Ontology Terms (11)
Functions (3)
Components (5)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Disease Associations ()
GWAS Traits (9)
Items per page:
1 – 5 of 9
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
7 | 6 | 3 | 1.1 | 91.5 | |||||
4 | 2 | 2 | 1.1 | 82 | |||||
Thyroid preparation use measurement | 1 | 1 | 1 | 70.2 | |||||
autoimmune thyroid disease | 1 | 1 | 0 | 1.1 | 69 | ||||
1 | 1 | 0 | 1.9 | 62.1 | |||||
Items per page:
1 – 5 of 9
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
3 | 1.1 | 91.5 | |||||
2 | 1.1 | 82 | |||||
Thyroid preparation use measurement | 1 | 70.2 | |||||
autoimmune thyroid disease | 0 | 1.1 | 69 | ||||
0 | 1.9 | 62.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | family with sequence similarity 98 member B | VGNC:11887 | 453315 | |||||
Macaque | family with sequence similarity 98 member B | 106999137 | ||||||
Mouse | MGI:1915465 | 68215 | ||||||
Rat | ||||||||
Dog | family with sequence similarity 98 member B | VGNC:40713 | 478254 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | family with sequence similarity 98 member B | |||||
Macaque | family with sequence similarity 98 member B | |||||
Mouse | ||||||
Rat | ||||||
Dog | family with sequence similarity 98 member B | |||||
Publication Statistics
PubMed Score 1.17
PubMed score by year
PubTator Score 0.62
PubTator score by year
Related Publications
Text Mined References (15)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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