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Tdark
ZCWPW2
Zinc finger CW-type PWWP domain protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000383768
  • ENSP00000373278
  • ENSG00000206559

Symbol
  • ZCW2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.74
tissue sample
0.63
tissue
0.57
cell line
0.5
cell type or tissue
0.42


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.71   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.71   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil percentage of leukocytes
1
1
1
31.7
lymphocyte count
1
1
1
7.5
monocyte count
1
1
1
7.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil percentage of leukocytes
1
31.7
lymphocyte count
1
7.5
monocyte count
1
7.5
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CW-type and PWWP domain containing 2
VGNC:8020
460240
Macaque
zinc finger CW-type and PWWP domain containing 2
702617
Dog
zinc finger CW-type and PWWP domain containing 2
100682830
Horse
zinc finger CW-type and PWWP domain containing 2
100058400
Cow
zinc finger CW-type and PWWP domain containing 2
789632
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CW-type and PWWP domain containing 2
Macaque
zinc finger CW-type and PWWP domain containing 2
Dog
zinc finger CW-type and PWWP domain containing 2
Horse
zinc finger CW-type and PWWP domain containing 2
Cow
zinc finger CW-type and PWWP domain containing 2
Protein Structure (3 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q504Y3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 3 of 3
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (5)
1 – 5 of 5
CFAP44
Tbio
Novelty: 0.17373896
Score: 0.533
Data Source: STRINGDB
RIC3
Tbio
Novelty: 0.0162412
Score: 0.444
Data Source: STRINGDB
ANKS6
Tbio
Novelty: 0.05822758
Score: 0.429
Data Source: STRINGDB
EPC1
Tbio
Novelty: 0.03216371
Score: 0.422
Data Source: STRINGDB
MORC3
Tbio
Novelty: 0.01216555
Score: 0.4
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.71

PubMed score by year
PubTator Score  0.31

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer