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Tdark
ATP13A4
Probable cation-transporting ATPase 13A4

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.83   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 3   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.83   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 3   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
ZNF169
Tdark
Family:  TF
Novelty:  1.09432767
Score:  0.67
Data Source:  STRINGDB
AGPAT2
Tchem
Family:  Enzyme
Novelty:  0.01321334
Score:  0.653
Data Source:  STRINGDB
NARS2
Tbio
Family:  Enzyme
Novelty:  0.01879317
Score:  0.608
Data Source:  STRINGDB
PRRT3
Tdark
Novelty:  0.32860844
Score:  0.605
Data Source:  STRINGDB
TMEM151B
Tdark
Novelty:  2.15276454
Score:  0.586
Data Source:  STRINGDB
KIAA0319
Tbio
Novelty:  0.01425914
Score:  0.552
Data Source:  STRINGDB
DPH6
Tbio
Family:  Enzyme
Novelty:  0.15211179
Score:  0.543
Data Source:  STRINGDB
ACBD7
Tdark
Novelty:  0.32019061
Score:  0.534
Data Source:  STRINGDB
SLC38A4
Tbio
Family:  Transporter
Novelty:  0.015839
Score:  0.522
Data Source:  STRINGDB
PM20D1
Tdark
Family:  Enzyme
Novelty:  0.07205788
Score:  0.519
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Ion channel transport (R-HSA-983712)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Ion channel transport
Reactome
Ion transport by P-type ATPases
Reactome
Transport of small molecules
Name
Explore in Pharos
Explore in Source
Ion channel transport
Ion transport by P-type ATPases
Transport of small molecules
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
salivary metabolite measurement
1
1
1
60.5
1
1
1
46.5
mathematical ability
2
2
2
37.3
dentures
2
1
2
35
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
salivary metabolite measurement
1
60.5
1
46.5
mathematical ability
2
37.3
dentures
2
35
1
33.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ATPase 13A4
VGNC:1742
460940
Macaque
ATPase 13A4
698284
Mouse
MGI:1924456
224079
Rat
RGD:1306927
288026
Dog
ATPase 13A4
VGNC:38244
100855915
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ATPase 13A4
Macaque
ATPase 13A4
Mouse
Rat
Dog
ATPase 13A4
Publication Statistics
PubMed Score 5.83
PubMed score by year
PubTator Score 2.96
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title