Tbio CDON Cell adhesion molecule-related/down-regulated by oncogenes

Protein Summary

Description

Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity). This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011]

Uniprot Accession IDs

• Q4KMG0
• O14631

Gene Name

• CDON

Ensembl ID

• ENST00000263577
• ENSP00000263577
• ENSG00000064309
• ENST00000392693
• ENSP00000376458

Symbol

• CDO
• CDO
• CDON1
• HPE11
• ORCAM

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.85
protein domain	0.85
microRNA	0.75
small molecule perturbation	0.75
transcription factor perturbation	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 593.22   (req: < 5)

Gene RIFs: 15   (req: <= 3)

Antibodies: 178   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 593.22   (req: >= 5)

Gene RIFs: 15   (req: > 3)

Antibodies: 178   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 19

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0