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Tbio
HSF5
Heat shock factor protein 5

Protein Summary
Description
May act as a transcriptional factor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000323777
  • ENSP00000313243
  • ENSG00000176160
  • ENST00000617946
  • ENSP00000484295

Symbol
  • HSTF5
  • HSF 5
  • HSTF 5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.68
cell type or tissue
0.64
phenotype
0.58
protein domain
0.58
cell line
0.56


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.84   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.84   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
2
2
2
87.5
ferritin measurement
1
1
1
83.8
monocyte percentage of leukocytes
1
1
1
81.4
intelligence
3
5
1
6.2
77.9
monocyte count
1
1
1
77.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
2
87.5
ferritin measurement
1
83.8
monocyte percentage of leukocytes
1
81.4
intelligence
1
6.2
77.9
monocyte count
1
77.3
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
heat shock transcription factor 5
VGNC:9328
455156
Macaque
heat shock transcription factor 5
714512
Mouse
MGI:2685585
327992
Dog
heat shock transcription factor 5
VGNC:41817
610000
Horse
heat shock transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:26862]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
heat shock transcription factor 5
Macaque
heat shock transcription factor 5
Mouse
Dog
heat shock transcription factor 5
Horse
heat shock transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:26862]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q4G112-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Model (ISM)
NTNU_SB
Protein-Protein Interactions (35)
1 – 10 of 35
HSF2BP
Tbio
Novelty:  0.18601995
Score:  0.761
Data Source:  STRINGDB
C5orf58
Tdark
Novelty:  39
Score:  0.655
Data Source:  STRINGDB
ADAM32
Tdark
Family:  Enzyme
Novelty:  0.36071191
Score:  0.621
Data Source:  STRINGDB
HSPB7
Tbio
Novelty:  0.03344805
Score:  0.612
Data Source:  STRINGDB
DENND2D
Tbio
Novelty:  0.16496649
Score:  0.57
Data Source:  STRINGDB
DNAJB1
Tbio
Novelty:  0.00139956
Score:  0.561
Data Source:  STRINGDB
GTSF1L
Tdark
Novelty:  8.10289389
Score:  0.553
Data Source:  STRINGDB
CCDC39
Tbio
Novelty:  0.0150835
Score:  0.545
Data Source:  STRINGDB
HEATR9
Tdark
Novelty:  0.71415315
Score:  0.534
Data Source:  STRINGDB
DOCK5
Tbio
Novelty:  0.03153692
Score:  0.531
Data Source:  STRINGDB
Publication Statistics
PubMed Score  17.84

PubMed score by year
PubTator Score  5.57

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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