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Tdark
ZFP69
Zinc finger protein 69 homolog

Protein Summary
Description
Putative transcription factor that appears to regulate lipid metabolism.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372705
  • ENSP00000361790
  • ENSG00000187815
  • ENST00000372706
  • ENSP00000361791

Symbol
  • ZNF642
  • ZFP69A
  • ZNF642
  • ZSCAN54A
  • ZKSCAN23A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
cell line
0.58
protein domain
0.58
phenotype
0.56
cell type or tissue
0.53


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.06   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 34   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.06   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
42.3
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ZFP69 zinc finger protein
VGNC:8134
469294
Macaque
ZFP69 zinc finger protein
694407
Mouse
MGI:107794
381549
Rat
Cow
ZFP69 zinc finger protein
VGNC:37168
521549
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ZFP69 zinc finger protein
Macaque
ZFP69 zinc finger protein
Mouse
Rat
Cow
ZFP69 zinc finger protein
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q49AA0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (21)
1 – 10 of 21
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.906
Data Source:  STRINGDB
ZDHHC23
Tbio
Family:  Enzyme
Novelty:  0.18700442
Score:  0.705
Data Source:  STRINGDB
TBC1D1
Tbio
Novelty:  0.0122464
Score:  0.665
Data Source:  STRINGDB
SORCS1
Tbio
Novelty:  0.03148473
Score:  0.644
Data Source:  STRINGDB
ILDR2
Tdark
Novelty:  0.2099634
Score:  0.588
Data Source:  STRINGDB
TMCO2
Tdark
Novelty:  0.18671657
Score:  0.576
Data Source:  STRINGDB
SMAP2
Tbio
Novelty:  0.70006863
Score:  0.533
Data Source:  STRINGDB
CCDC39
Tbio
Novelty:  0.0150835
Score:  0.531
Data Source:  STRINGDB
TERB1
Tdark
Family:  TF
Novelty:  0.20863595
Score:  0.525
Data Source:  STRINGDB
TOX4
Tbio
Family:  TF
Novelty:  0.02486844
Score:  0.515
Data Source:  STRINGDB
Publication Statistics
PubMed Score  3.06

PubMed score by year
PubTator Score  1.67

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer