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Tbio
GALNTL6
Polypeptide N-acetylgalactosaminyltransferase-like 6

Protein Summary
Description
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000506823
  • ENSP00000423313
  • ENSG00000174473
  • ENST00000508122
  • ENSP00000423827

Symbol
  • GALNT17
  • GALNT17
  • GALNACT20
  • GalNAc-T6L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
histone modification site profile
0.68
phenotype
0.68
cell type or tissue
0.64
disease
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.83   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.83   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
C1GALT1
Tbio
Family:  Enzyme
Novelty:  0.01191596
Score:  0.959
Data Source:  STRINGDB
MUC5AC
Tbio
Novelty:  0.00074159
Score:  0.938
Data Source:  STRINGDB
MUC1
Tchem
Novelty:  0.00024203
Score:  0.937
Data Source:  STRINGDB
MUC6
Tbio
Novelty:  0.00304872
Score:  0.928
Data Source:  STRINGDB
MUC5B
Tbio
Novelty:  0.000832
Score:  0.924
Data Source:  STRINGDB
MUC20
Tbio
Novelty:  0.04645313
Score:  0.923
Data Source:  STRINGDB
MUC4
Tbio
Novelty:  0.00193208
Score:  0.919
Data Source:  STRINGDB
MUC12
Tbio
Novelty:  0.04323645
Score:  0.911
Data Source:  STRINGDB
MUC16
Tbio
Novelty:  0.00444587
Score:  0.91
Data Source:  STRINGDB
MUC7
Tbio
Novelty:  0.00750654
Score:  0.909
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
O-linked glycosylation
Reactome
O-linked glycosylation of mucins
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
O-linked glycosylation
O-linked glycosylation of mucins
Post-translational protein modification
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking behavior
1
1
1
52.4
smoking status measurement
1
1
1
38.8
body mass index
1
1
1
36.9
self reported educational attainment
1
1
1
3.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking behavior
1
52.4
smoking status measurement
1
38.8
body mass index
1
36.9
self reported educational attainment
1
3.7
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
polypeptide N-acetylgalactosaminyltransferase like 6
VGNC:50350
471350
Macaque
polypeptide N-acetylgalactosaminyltransferase like 6
695898
Mouse
MGI:1913581
270049
Rat
RGD:1564773
361142
Dog
polypeptide N-acetylgalactosaminyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:33844]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
polypeptide N-acetylgalactosaminyltransferase like 6
Macaque
polypeptide N-acetylgalactosaminyltransferase like 6
Mouse
Rat
Dog
polypeptide N-acetylgalactosaminyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:33844]
Publication Statistics
PubMed Score 3.83
PubMed score by year
PubTator Score 1.29
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title