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Tdark
CCDC153
Coiled-coil domain-containing protein 153

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000415318
  • ENSP00000445431
  • ENSG00000248712
  • ENST00000503566
  • ENSP00000423567
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.78
gene perturbation
0.68
cell type or tissue
0.61
tissue sample
0.59
cell line
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 103   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.12   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 103   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
2
3
85.9
platelet crit
2
3
4
74
sex hormone-binding globulin measurement
2
1
2
37
monocyte count
1
1
1
32.8
lymphocyte count
1
1
1
32.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
85.9
platelet crit
4
74
sex hormone-binding globulin measurement
2
37
monocyte count
1
32.8
lymphocyte count
1
32.8
Protein-Protein Interactions (6)
1 – 6 of 6
TXLNB
Tbio
Novelty: 0.12751933
Score: 0.521
Data Source: STRINGDB
STX19
Tdark
Novelty: 0.99387951
Score: 0.518
Data Source: STRINGDB
CCDC33
Tdark
Novelty: 0.17166818
Score: 0.513
Data Source: STRINGDB
MUSTN1
Tdark
Novelty: 0.19678276
Score: 0.49
Data Source: STRINGDB
DNASE2B
Tbio
Family: Enzyme
Novelty: 0.02506932
Score: 0.441
Data Source: STRINGDB
LRRC17
Tdark
Novelty: 0.16875862
Score: 0.418
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.12

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer