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Tdark
ZIK1
Zinc finger protein interacting with ribonucleoprotein K

Protein Summary
Description
May be a transcriptional repressor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000597850
  • ENSP00000472867
  • ENSG00000171649
  • ENST00000599456
  • ENSP00000468937

Symbol
  • ZNF762
  • ZNF762
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.78
virus perturbation
0.72
tissue
0.63
protein domain
0.58
microRNA
0.56


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 96   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 96   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
3
4
90.6
mean reticulocyte volume
1
1
1
62.1
balding measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
90.6
mean reticulocyte volume
1
62.1
balding measurement
1
24.5
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein interacting with K protein 1
VGNC:13122
456331
Macaque
zinc finger protein interacting with K protein 1
708621
Mouse
MGI:108070
22775
Rat
RGD:6494420
100911224
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein interacting with K protein 1
Macaque
zinc finger protein interacting with K protein 1
Mouse
Rat
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q3SY52-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (17)
1 – 10 of 17
GTF2IRD1
Tbio
Family:  TF
Novelty:  0.01858027
p_int:  0.997270013
p_ni:  0.002729624
p_wrong:  3.63e-7
Data Source:  BioPlex
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.908
Data Source:  STRINGDB
CXorf40B
Tdark
Novelty:  10.83333333
Score:  0.577
Data Source:  STRINGDB
PNMA5
Tdark
Novelty:  0.38868015
Score:  0.569
Data Source:  STRINGDB
GJA9
Tbio
Novelty:  0.17967582
Score:  0.549
Data Source:  STRINGDB
PNMA3
Tbio
Novelty:  0.00582151
Score:  0.516
Data Source:  STRINGDB
H2BFM
Tdark
Novelty:  1.7560547
Score:  0.501
Data Source:  STRINGDB
CCSAP
Tbio
Novelty:  0.0205986
Score:  0.478
Data Source:  STRINGDB
WFDC12
Tbio
Novelty:  0.14304609
Score:  0.448
Data Source:  STRINGDB
SDR42E1
Tdark
Family:  Enzyme
Novelty:  2.41213299
Score:  0.435
Data Source:  STRINGDB
Publication Statistics
PubMed Score  5.00

PubMed score by year
PubTator Score  1.78

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer