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Tdark
ZNF718
Zinc finger protein 718

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.19   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.19   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (11)
1 – 10 of 11
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.904
Data Source:  STRINGDB
FAM181A
Tdark
Novelty:  0.6096481
Score:  0.54
Data Source:  STRINGDB
ASB13
Tdark
Novelty:  0.50667757
Score:  0.495
Data Source:  STRINGDB
SLC49A3
Tdark
Novelty:  2.10091159
Score:  0.473
Data Source:  STRINGDB
SYTL3
Tbio
Novelty:  0.04849748
Score:  0.45
Data Source:  STRINGDB
MAN2B2
Tbio
Family:  Enzyme
Novelty:  0.11499103
Score:  0.443
Data Source:  STRINGDB
BEX5
Tdark
Novelty:  0.2964824
Score:  0.442
Data Source:  STRINGDB
SIK1B
Tdark
Novelty:  0.44606625
Score:  0.442
Data Source:  STRINGDB
SGCZ
Tbio
Novelty:  0.08511312
Score:  0.424
Data Source:  STRINGDB
ARL15
Tbio
Family:  Enzyme
Novelty:  0.09327102
Score:  0.414
Data Source:  STRINGDB
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cerebrospinal fluid biomarker measurement
1
1
0
20.5
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cerebrospinal fluid biomarker measurement
0
20.5
31.4
Publication Statistics
PubMed Score 1.19
PubMed score by year
PubTator Score 0.58
PubTator score by year