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Tdark
ZSCAN23
Zinc finger and SCAN domain-containing protein 23

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000289788
  • ENSP00000289788
  • ENSG00000187987

Symbol
  • ZNF390
  • ZNF453
  • ZNF390
  • ZNF453
  • dJ29K1.3
  • dJ29K1.3.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
histone modification site profile
0.64
tissue sample
0.56
disease
0.53
tissue
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.65   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.65   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (33)
1 – 10 of 33
ZSCAN32
Tdark
Family:  TF
Novelty:  3.83392226
p_int:  0.999545133
p_ni:  4.92e-7
p_wrong:  0.000454376
Score:  0.69
Data Source:  BioPlex,STRINGDB
ZSCAN20
Tdark
Family:  TF
Novelty:  0.37441538
p_int:  0.999082149
p_ni:  5.6e-7
p_wrong:  0.000917291
Score:  0.653
Data Source:  BioPlex,STRINGDB
TRIM40
Tbio
Novelty:  0.26950973
Score:  0.823
Data Source:  STRINGDB
ZKSCAN7
Tbio
Family:  TF
Novelty:  0.00670558
Score:  0.809
Data Source:  STRINGDB
VARS2
Tbio
Family:  Enzyme
Novelty:  0.00941946
Score:  0.78
Data Source:  STRINGDB
TRIM10
Tbio
Novelty:  0.27685659
Score:  0.774
Data Source:  STRINGDB
UHRF1BP1L
Tbio
Novelty:  0.55650495
Score:  0.773
Data Source:  STRINGDB
ZSCAN21
Tbio
Family:  TF
Novelty:  0.18025344
Score:  0.725
Data Source:  STRINGDB
ZSCAN22
Tdark
Family:  TF
Novelty:  0.79698385
Score:  0.713
Data Source:  STRINGDB
PTPN22
Tchem
Family:  Enzyme
Novelty:  0.00168847
Score:  0.666
Data Source:  STRINGDB
GWAS Traits (30)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
4
0
1.2
93.7
wellbeing measurement
3
4
4
89.6
major depressive disorder
2
2
1
8.9
86.6
peak expiratory flow
1
1
1
83.9
2
2
0
5
83.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
93.7
wellbeing measurement
4
89.6
major depressive disorder
1
8.9
86.6
peak expiratory flow
1
83.9
0
5
83.6
Find similar targets by:
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 23
VGNC:7951
471919
Macaque
zinc finger and SCAN domain containing 23
707677
Dog
zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]
Horse
zinc finger and SCAN domain containing 23
VGNC:52473
100061358
Cow
zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 23
Macaque
zinc finger and SCAN domain containing 23
Dog
zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]
Horse
zinc finger and SCAN domain containing 23
Cow
zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]
Publication Statistics
PubMed Score 0.65
PubMed score by year
PubTator Score 0.25
PubTator score by year