HLA-DRB5
HLA class II histocompatibility antigen, DR beta 5 chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
phenotype | 0.96 | ||
protein domain | 0.92 | ||
disease perturbation | 0.87 | ||
cellular component | 0.83 | ||
disease | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Costimulation by the CD28 family | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Downstream TCR signaling | ||||
Reactome | Generation of second messenger molecules | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Costimulation by the CD28 family | ||||
Cytokine Signaling in Immune system | ||||
Downstream TCR signaling | ||||
Generation of second messenger molecules | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
10 | 10 | 3 | 2.1 | 99.7 | |||||
6 | 6 | 0 | 2.5 | 99.2 | |||||
eosinophil count | 4 | 4 | 5 | 98.1 | |||||
neutrophil count | 4 | 4 | 4 | 98.1 | |||||
8 | 5 | 0 | 1.5 | 98 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
3 | 2.1 | 99.7 | |||||
0 | 2.5 | 99.2 | |||||
eosinophil count | 5 | 98.1 | |||||
neutrophil count | 4 | 98.1 | |||||
0 | 1.5 | 98 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | major histocompatibility complex, class II, DR beta 5 | 462592 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | major histocompatibility complex, class II, DR beta 5 | |||||
PMID | Year | Title |
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