Tdark COL28A1 Collagen alpha-1(XXVIII) chain

Protein Summary

Description

May act as a cell-binding protein. COL28A1 belongs to a class of collagens containing von Willebrand factor (VWF; MIM 613160) type A (VWFA) domains (Veit et al., 2006 [PubMed 16330543]).[supplied by OMIM, Nov 2010]

Uniprot Accession IDs

• Q2UY09
• A4D101
• A4D106
• A4D107
• A8MVR2
• B9EGX9
• Q2UY07
• Q2UY08

Gene Name

• COL28A1

Ensembl ID

• ENST00000399429
• ENSP00000382356
• ENSG00000215018

Symbol

• COL28
• COL28

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.7
tissue	0.62
protein domain	0.58
phenotype	0.57
cell line	0.56

Protein Classes

PANTHER Classes

Protein / Extracellular Matrix Protein / Extracellular Matrix Structural Protein / Collagen Alpha-1(xxviii) Chain

DTO Classes

Protein / Extracellular Structure / Extracellular Matrix Structural Protein / Collagen Alpha-1(xxviii) Chain

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.14   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 18   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.14   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0