Tbio HKDC1 Putative hexokinase HKDC1

Protein Summary

Description

This gene encodes a member of the hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma. [provided by RefSeq, Sep 2016]

Uniprot Accession IDs

• Q2TB90
• B5MDN9
• Q2TB91
• Q5VTC7
• Q7Z373
• Q8WU37
• Q96EH2
• Q9H5Y9

Gene Name

• HKDC1

Ensembl ID

• ENST00000354624
• ENSP00000346643
• ENSG00000156510

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.94
gene perturbation	0.78
interacting protein	0.7
transcription factor perturbation	0.68
tissue sample	0.63

Protein Classes

DTO Classes

Protein / Kinase / Unclassified Protein / Putative Hexokinase Hkdc1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 66.92   (req: < 5)

Gene RIFs: 17   (req: <= 3)

Antibodies: 130   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 66.92   (req: >= 5)

Gene RIFs: 17   (req: > 3)

Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0