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Tdark
ZNF800
Zinc finger protein 800

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265827
  • ENSP00000265827
  • ENSG00000048405
  • ENST00000393312
  • ENSP00000376988
  • ENST00000393313
  • ENSP00000376989
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
transcription factor perturbation
0.74
microRNA
0.73
transcription factor binding site profile
0.7
tissue sample
0.63


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.8   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.8   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
2
5
92.4
2
2
1
1.1
83.8
red blood cell distribution width
2
2
2
82.9
lymphocyte percentage of leukocytes
1
2
2
81.2
appendicular lean mass
4
1
4
78.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
5
92.4
1
1.1
83.8
red blood cell distribution width
2
82.9
lymphocyte percentage of leukocytes
2
81.2
appendicular lean mass
4
78.1
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 800
VGNC:4586
463695
Macaque
zinc finger protein 800
697855
Mouse
MGI:1889334
627049
Rat
RGD:1560157
500057
Dog
zinc finger protein 800
VGNC:48823
475207
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 800
Macaque
zinc finger protein 800
Mouse
Rat
Dog
zinc finger protein 800
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2TB10-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (26)
1 – 10 of 26
RRP8
Tbio
Family:  Enzyme
Novelty:  0.04922797
p_int:  0.998692513
p_ni:  0.001307467
p_wrong:  2e-8
Score:  0.514
Data Source:  BioPlex,STRINGDB
PRR11
Tbio
Novelty:  0.05077483
p_int:  0.995697892
p_ni:  0.004297225
p_wrong:  0.000004884
Data Source:  BioPlex
ZNF2
Tbio
Family:  TF
Novelty:  0.01062543
p_int:  0.990880889
p_ni:  0.009110318
p_wrong:  0.000008793
Data Source:  BioPlex
NPM1
Tbio
Novelty:  0.0005485
p_int:  0.988505991
p_ni:  0.011494009
Score:  0.156
Data Source:  BioPlex,STRINGDB
MECP2
Tchem
Family:  TF
Novelty:  0.00051767
p_int:  0.987421459
p_ni:  0.012557177
p_wrong:  0.000021364
Data Source:  BioPlex
HDAC1
Tclin
Family:  Epigenetic
Novelty:  0.00065244
p_int:  0.984690888
p_ni:  0.015309112
Score:  0.28
Data Source:  BioPlex,STRINGDB
DGCR8
Tbio
Novelty:  0.00271221
p_int:  0.983937671
p_ni:  0.016041329
p_wrong:  0.000021
Data Source:  BioPlex
MTA2
Tbio
Family:  TF
Novelty:  0.01525806
p_int:  0.969843783
p_ni:  0.030156217
Score:  0.315
Data Source:  BioPlex,STRINGDB
MTA3
Tbio
Family:  TF
Novelty:  0.02667635
p_int:  0.963358888
p_ni:  0.036641111
p_wrong:  1e-9
Score:  0.666
Data Source:  BioPlex,STRINGDB
CNBP
Tbio
Novelty:  0.00404247
p_int:  0.945789036
p_ni:  0.005080793
p_wrong:  0.049130171
Data Source:  BioPlex
Publication Statistics
PubMed Score  2.80

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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