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Tdark
TSNAXIP1
Translin-associated factor X-interacting protein 1

Protein Summary
Description
Possible role in spermatogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000388833
  • ENSP00000373485
  • ENSG00000102904

Symbol
  • TXI1
  • TXI1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.79
cell type or tissue
0.66
cell line
0.58
tissue sample
0.54
small molecule perturbation
0.53


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.05   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.05   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
10
9
18
99.2
apolipoprotein A 1 measurement
2
3
3
97.1
hemoglobin measurement
3
3
3
92.7
hematocrit
3
3
3
91.8
stem Cell Factor measurement
1
1
1
83.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
18
99.2
apolipoprotein A 1 measurement
3
97.1
hemoglobin measurement
3
92.7
hematocrit
3
91.8
stem Cell Factor measurement
1
83.3
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
translin associated factor X interacting protein 1
VGNC:9199
454174
Macaque
translin associated factor X interacting protein 1
700095
Mouse
MGI:1919486
72236
Rat
RGD:1565341
498944
Dog
translin associated factor X interacting protein 1
VGNC:47909
479682
Species
Name
OMA
EggNOG
Inparanoid
Chimp
translin associated factor X interacting protein 1
Macaque
translin associated factor X interacting protein 1
Mouse
Rat
Dog
translin associated factor X interacting protein 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2TAA8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (21)
1 – 10 of 21
PIBF1
Tbio
Novelty:  0.0454209
p_int:  0.999999556
p_ni:  4.44e-7
Score:  0.197
Data Source:  BioPlex,STRINGDB
CCDC186
Tdark
Novelty:  0.44973807
p_int:  0.999999441
p_ni:  5.59e-7
Score:  0.282
Data Source:  BioPlex,STRINGDB
DPP8
Tchem
Family:  Enzyme
Novelty:  0.00678793
p_int:  0.994148922
p_ni:  0.005842297
p_wrong:  0.000008782
Score:  0.241
Data Source:  BioPlex,STRINGDB
FBXW5
Tbio
Novelty:  0.13100873
p_int:  0.992464542
p_ni:  0.006947629
p_wrong:  0.000587829
Score:  0.232
Data Source:  BioPlex,STRINGDB
USO1
Tbio
Novelty:  0.02066669
p_int:  0.837738429
p_ni:  0.162261571
Score:  0.188
Data Source:  BioPlex,STRINGDB
TSNAX
Tbio
Novelty:  0.00888891
Score:  0.889
Data Source:  STRINGDB
SMAGP
Tbio
Novelty:  0.2379422
Score:  0.621
Data Source:  STRINGDB
C8orf33
Tdark
Novelty:  1.51064136
Score:  0.585
Data Source:  STRINGDB
MITD1
Tbio
Novelty:  0.30899265
Score:  0.569
Data Source:  STRINGDB
GFOD2
Tdark
Family:  Enzyme
Novelty:  0.45929342
Score:  0.543
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.05

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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