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Tbio
RPEL1
Ribulose-phosphate 3-epimerase-like protein 1

Protein Summary
Description
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000441178
  • ENSP00000476672
  • ENSG00000235376
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.58
protein domain
0.58
tissue
0.52
cell line
0.39
biological process
0.38


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.56   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.56   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (25)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
4
5
89.7
6
4
2
1.2
86.2
reticulocyte measurement
1
1
1
80
systolic blood pressure
2
2
2
78.2
worry measurement
2
3
2
7.2
72.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
5
89.7
2
1.2
86.2
reticulocyte measurement
1
80
systolic blood pressure
2
78.2
worry measurement
2
7.2
72.1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2QD12-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (8)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Metabolism of carbohydrates
Reactome
Pentose phosphate pathway
Name
Explore in Pharos
Explore in Source
Metabolism
Metabolism of carbohydrates
Pentose phosphate pathway
Gene Ontology Terms (7)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Experiment (EXP)
Reactome
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (48)
1 – 10 of 48
RPIA
Tbio
Family:  Enzyme
Novelty:  0.00968705
Score:  0.981
Data Source:  STRINGDB
TKTL2
Tbio
Family:  Enzyme
Novelty:  0.0915871
Score:  0.98
Data Source:  STRINGDB
TKT
Tchem
Family:  Enzyme
Novelty:  0.00333936
Score:  0.978
Data Source:  STRINGDB
TKTL1
Tbio
Family:  Enzyme
Novelty:  0.01464511
Score:  0.97
Data Source:  STRINGDB
XYLB
Tbio
Family:  Kinase
Novelty:  0.00540687
Score:  0.965
Data Source:  STRINGDB
PGD
Tchem
Family:  Enzyme
Novelty:  0.00576529
Score:  0.961
Data Source:  STRINGDB
RPE
Tbio
Family:  Enzyme
Novelty:  0.01035554
Score:  0.801
Data Source:  STRINGDB
TALDO1
Tbio
Family:  Enzyme
Novelty:  0.00208619
Score:  0.794
Data Source:  STRINGDB
H6PD
Tbio
Novelty:  0.00366637
Score:  0.752
Data Source:  STRINGDB
FBP2
Tbio
Family:  Enzyme
Novelty:  0.00854851
Score:  0.7
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.56

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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