You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
C2orf68
UPF0561 protein C2orf68

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306336
  • ENSP00000304410
  • ENSG00000168887
  • ENST00000409734
  • ENSP00000386301

Symbol
  • HCRCN81
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.55   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 42   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.55   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 42   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
7
6
4
1.1
94.9
6
4
1
1.1
90
serum gamma-glutamyl transferase measurement
2
3
3
81.1
3
2
0
1.1
69.6
eosinophil count
3
1
3
62.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
1.1
94.9
1
1.1
90
serum gamma-glutamyl transferase measurement
3
81.1
0
1.1
69.6
eosinophil count
3
62.8
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1915614
68364
Rat
RGD:1587471
691113
Dog
chromosome 17 C2orf68 homolog
VGNC:49221
612043
Horse
chromosome 15 C2orf68 homolog
VGNC:51285
100067258
Cow
chromosome 11 C2orf68 homolog
VGNC:52617
616899
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
chromosome 17 C2orf68 homolog
Horse
chromosome 15 C2orf68 homolog
Cow
chromosome 11 C2orf68 homolog
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2NKX9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (28)
1 – 10 of 28
SMG6
Tbio
Family:  Enzyme
Novelty:  0.0217417
p_int:  0.999999947
p_ni:  5.3e-8
Score:  0.241
Data Source:  BioPlex,STRINGDB
GNE
Tbio
Family:  Enzyme
Novelty:  0.00285751
p_int:  0.999999886
p_ni:  1.12e-7
p_wrong:  3e-9
Score:  0.507
Data Source:  BioPlex,STRINGDB
PIR
Tchem
Novelty:  0.00327695
p_int:  0.999956631
p_ni:  0.000039701
p_wrong:  0.000003668
Score:  0.29
Data Source:  BioPlex,STRINGDB
DDHD2
Tbio
Family:  Enzyme
Novelty:  0.04306798
p_int:  0.99989911
p_ni:  0.000100887
p_wrong:  3e-9
Score:  0.228
Data Source:  BioPlex,STRINGDB
GMNN
Tbio
Novelty:  0.00436572
p_int:  0.999866382
p_ni:  0.000133612
p_wrong:  6e-9
Score:  0.204
Data Source:  BioPlex,STRINGDB
KLHL15
Tbio
Novelty:  0.54712519
p_int:  0.995693639
p_ni:  0.004306361
Data Source:  BioPlex
HSPA9
Tchem
Novelty:  0.00235171
p_int:  0.766389905
p_ni:  0.233610095
Score:  0.19
Data Source:  BioPlex,STRINGDB
TMEM150A
Tbio
Novelty:  0.12446897
Score:  0.83
Data Source:  STRINGDB
PSD4
Tbio
Novelty:  0.0674237
Score:  0.725
Data Source:  STRINGDB
USP39
Tbio
Novelty:  0.03914006
Score:  0.685
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.55

PubMed score by year
PubTator Score  0.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer