Protein Summary
May be involved in transcriptional regulation. This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
- ENST00000414387
- ENSP00000428248
- ENSG00000251192
- ENST00000523374
- ENSP00000429148
- MRX92
- ZNF673B
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.8 | ||
histone modification site profile | 0.76 | ||
microRNA | 0.62 | ||
protein domain | 0.58 | ||
tissue sample | 0.48 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.67 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 87 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.67 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 87 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0