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Tdark
ZNF674
Zinc finger protein 674

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000414387
  • ENSP00000428248
  • ENSG00000251192
  • ENST00000523374
  • ENSP00000429148

Symbol
  • MRX92
  • ZNF673B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.8
histone modification site profile
0.76
microRNA
0.62
protein domain
0.58
tissue sample
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.13   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.13   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (21)
1 – 10 of 21
ZNF385B
Tbio
Novelty: 0.14389498
Score: 0.806
Data Source: STRINGDB
CHST7
Tbio
Family: Enzyme
Novelty: 0.18769086
Score: 0.748
Data Source: STRINGDB
SLC9A7
Tbio
Family: Transporter
Novelty: 0.03560989
Score: 0.647
Data Source: STRINGDB
NBPF10
Tdark
Novelty: 0.44885173
Score: 0.567
Data Source: STRINGDB
FCHO1
Tbio
Novelty: 0.10512826
Score: 0.546
Data Source: STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.545
Data Source: STRINGDB
CLHC1
Tdark
Novelty: 3.14766818
Score: 0.532
Data Source: STRINGDB
NXF5
Tbio
Novelty: 0.18468434
Score: 0.522
Data Source: STRINGDB
DLG3
Tbio
Novelty: 0.01196565
Score: 0.518
Data Source: STRINGDB
C1orf109
Tdark
Novelty: 0.93042195
Score: 0.514
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.13

PubMed score by year
PubTator Score  1.75

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer