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Tbio
SLC35G1
Solute carrier family 35 member G1

Protein Summary
Description
May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell. This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371408
  • ENSP00000360462
  • ENSG00000176273
  • ENST00000427197
  • ENSP00000400932

Symbol
  • C10orf60
  • POST
  • TMEM20
  • POST
  • TMEM20
  • C10orf60
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.73
microRNA
0.68
tissue sample
0.65
cell type or tissue
0.55
transcription factor
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 60.17   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 60.17   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
STIM1
Tbio
Novelty:  0.00116516
Score:  0.759
Data Source:  STRINGDB
NOC3L
Tbio
Novelty:  0.05635731
Score:  0.75
Data Source:  STRINGDB
YIPF1
Tbio
Novelty:  0.00507381
Score:  0.728
Data Source:  STRINGDB
TNKS2
Tchem
Family:  Enzyme
Novelty:  0.00938509
Score:  0.674
Data Source:  STRINGDB
PPP1R3C
Tbio
Family:  Enzyme
Novelty:  0.01784199
Score:  0.67
Data Source:  STRINGDB
STIMATE
Tbio
Novelty:  0.28975783
Score:  0.642
Data Source:  STRINGDB
SLC35E2B
Tdark
Family:  Transporter
Novelty:  1.15253216
Score:  0.623
Data Source:  STRINGDB
SLC35E2A
Tdark
Family:  Transporter
Novelty:  1.16292212
Score:  0.623
Data Source:  STRINGDB
PLCE1
Tbio
Family:  Enzyme
Novelty:  0.0070258
Score:  0.618
Data Source:  STRINGDB
HECTD2
Tbio
Family:  Enzyme
Novelty:  7.27062916
Score:  0.591
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aortic measurement
2
2
2
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aortic measurement
2
49.5
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member G1
VGNC:5784
466164
Mouse
MGI:2444789
240660
Rat
RGD:1595908
294072
Dog
solute carrier family 35 member G1
VGNC:53012
100856181
Horse
solute carrier family 35 member G1
VGNC:23178
100071133
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member G1
Mouse
Rat
Dog
solute carrier family 35 member G1
Horse
solute carrier family 35 member G1
Publication Statistics
PubMed Score 60.17
PubMed score by year
PubTator Score 241.78
PubTator score by year
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Related Publications
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PMID
Year
Title