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Tbio
SLC5A9
Sodium/glucose cotransporter 4

Protein Summary
Description
Involved in sodium-dependent transport of D-mannose, D-glucose and D-fructose.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000236495
  • ENSP00000236495
  • ENSG00000117834
  • ENST00000438567
  • ENSP00000401730
  • ENST00000533824
  • ENSP00000431900

Symbol
  • SGLT4
  • SGLT4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.74
tissue sample
0.56
microRNA
0.53
cellular component
0.52
pathway
0.52


Related Tools
RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.39   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.39   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 5 member 9
VGNC:8114
743632
Macaque
solute carrier family 5 member 9
713064
Mouse
MGI:2140201
230612
Rat
RGD:1311383
366441
Dog
solute carrier family 5 member 9
VGNC:46452
482502
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 5 member 9
Macaque
solute carrier family 5 member 9
Mouse
Rat
Dog
solute carrier family 5 member 9
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2M3M2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (11)
Cellular hexose transport (R-HSA-189200)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cellular hexose transport
Reactome
SLC-mediated transmembrane transport
Reactome
Transport of small molecules
Name
Explore in Pharos
Explore in Source
Cellular hexose transport
SLC-mediated transmembrane transport
Transport of small molecules
Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (26)
1 – 10 of 26
TRABD2B
Tbio
Family: Enzyme
Novelty: 0.12802951
Score: 0.762
Data Source: STRINGDB
CDH16
Tbio
Novelty: 0.03884426
Score: 0.62
Data Source: STRINGDB
SLC2A2
Tchem
Family: Transporter
Novelty: 0.00103579
Score: 0.608
Data Source: STRINGDB
SLC13A3
Tbio
Family: Transporter
Novelty: 0.02627177
Score: 0.602
Data Source: STRINGDB
SLC7A13
Tdark
Family: Transporter
Novelty: 0.20907223
Score: 0.586
Data Source: STRINGDB
SLC2A5
Tbio
Family: Transporter
Novelty: 0.0032733
Score: 0.576
Data Source: STRINGDB
TRABD2A
Tbio
Family: Enzyme
Novelty: 0.23707192
Score: 0.535
Data Source: STRINGDB
TMEM150A
Tbio
Novelty: 0.12446897
Score: 0.525
Data Source: STRINGDB
SLC16A7
Tchem
Family: Transporter
Novelty: 0.00725474
Score: 0.524
Data Source: STRINGDB
SLC2A8
Tbio
Family: Transporter
Novelty: 0.02075375
Score: 0.523
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.39

PubMed score by year
PubTator Score  5.22

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer