Protein Summary
May be involved in transcriptional regulation. This gene encodes a protein containing an N-terminal Kruppel-associated box-containing (KRAB) domain and 13 Kruppel-type C2H2 zinc finger domains. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
- ENST00000409324
- ENSP00000386393
- ENSG00000221994
- ENST00000442455
- ENSP00000393163
- dJ54B20.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.7 | ||
tissue sample | 0.65 | ||
protein domain | 0.58 | ||
tissue | 0.49 | ||
biological process | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.9 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 50 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.9 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 50 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (14)
Nearest Tclin Targets
Pathways (1)
KEGG (1)
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
KEGG | Herpes simplex virus 1 infection | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Herpes simplex virus 1 infection | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (2)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (3)
1 – 3 of 3
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Macaque | zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855] | |||||||
Dog | zinc finger protein 630 | VGNC:48780 | 491865 | |||||
Horse | zinc finger protein 630 | VGNC:25364 | 100061608 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Macaque | zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855] | |||||
Dog | zinc finger protein 630 | |||||
Horse | zinc finger protein 630 | |||||
Publication Statistics
PubMed Score 0.90
PubMed score by year
PubTator Score 1.00
PubTator score by year
Related Publications
Text Mined References (4)
GeneRif Annotations (2)
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