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Tdark
ZNF630
Zinc finger protein 630

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein containing an N-terminal Kruppel-associated box-containing (KRAB) domain and 13 Kruppel-type C2H2 zinc finger domains. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000409324
  • ENSP00000386393
  • ENSG00000221994
  • ENST00000442455
  • ENSP00000393163

Symbol
  • dJ54B20.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.7
tissue sample
0.65
protein domain
0.58
tissue
0.49
biological process
0.41


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.9   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.9   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (14)
SPACA5
Tdark
Family:  Enzyme
Novelty:  0.19829871
Score:  0.725
Data Source:  STRINGDB
CFAP47
Tdark
Novelty:  0.59170159
Score:  0.58
Data Source:  STRINGDB
CXorf40A
Tbio
Novelty:  0.13576501
Score:  0.575
Data Source:  STRINGDB
ITIH6
Tdark
Novelty:  4.5922884
Score:  0.558
Data Source:  STRINGDB
INTS6L
Tdark
Novelty:  1.91229606
Score:  0.518
Data Source:  STRINGDB
GPKOW
Tbio
Novelty:  0.14830491
Score:  0.504
Data Source:  STRINGDB
H2BFM
Tdark
Novelty:  1.7560547
Score:  0.492
Data Source:  STRINGDB
H2BFWT
Tbio
Novelty:  0.16138632
Score:  0.491
Data Source:  STRINGDB
ASB9
Tbio
Novelty:  0.18287435
Score:  0.488
Data Source:  STRINGDB
OR6C6
Tdark
Family:  oGPCR
Novelty:  48
Score:  0.476
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855]
Dog
zinc finger protein 630
VGNC:48780
491865
Horse
zinc finger protein 630
VGNC:25364
100061608
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855]
Dog
zinc finger protein 630
Horse
zinc finger protein 630
Publication Statistics
PubMed Score 0.90
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title