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Tdark
PRSS53
Serine protease 53

Protein Summary
Description
In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000280606
  • ENSP00000280606
  • ENSG00000151006

Symbol
  • POL3S
  • UNQ308
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.82
small molecule perturbation
0.61
protein domain
0.58
tissue sample
0.51
cell line
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.97   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 29   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.97   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 29   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0