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Tdark
GSG1
Germ cell-specific gene 1 protein

Protein Summary
Description
May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000337630
  • ENSP00000336816
  • ENSG00000111305
  • ENST00000396302
  • ENSP00000379596
  • ENST00000432710
  • ENSP00000405032
  • ENST00000457134
  • ENSP00000398384
  • ENST00000537302
  • ENSP00000441718
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.7
transcription factor
0.62
cellular component
0.6
PubMedID
0.56
cell type or tissue
0.54


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.56   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.56   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
5
10
98
serum albumin measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
10
98
serum albumin measurement
1
24.5
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
germ cell associated 1
VGNC:5408
465302
Macaque
germ cell associated 1
698194
Mouse
MGI:1194499
14840
Rat
RGD:1306546
312793
Dog
germ cell associated 1
VGNC:41528
486677
Species
Name
OMA
EggNOG
Inparanoid
Chimp
germ cell associated 1
Macaque
germ cell associated 1
Mouse
Rat
Dog
germ cell associated 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q2KHT4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (19)
1 – 10 of 19
IL37
Tbio
Novelty:  0.00499186
p_int:  0.892439433
p_ni:  0.107559301
p_wrong:  0.000001266
Score:  0.379
Data Source:  BioPlex,STRINGDB
ASAH1
Tchem
Family:  Enzyme
Novelty:  0.00374228
p_int:  0.858386254
p_ni:  0.141613087
p_wrong:  6.59e-7
Score:  0.241
Data Source:  BioPlex,STRINGDB
ATP4A
Tclin
Family:  Transporter
Novelty:  0.00008783
Score:  0.652
Data Source:  STRINGDB
ARFIP2
Tbio
Novelty:  0.01200959
Score:  0.536
Data Source:  STRINGDB
SHISA9
Tbio
Novelty:  0.10986428
Score:  0.536
Data Source:  STRINGDB
FHL5
Tbio
Novelty:  0.27618006
Score:  0.515
Data Source:  STRINGDB
NRN1
Tbio
Novelty:  0.01198116
Score:  0.514
Data Source:  STRINGDB
PPID
Tchem
Family:  Enzyme
Novelty:  0.01068886
Score:  0.493
Data Source:  STRINGDB
C10orf62
Tdark
Novelty:  12.75
Score:  0.488
Data Source:  STRINGDB
VWC2
Tdark
Novelty:  0.30211591
Score:  0.483
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.56

PubMed score by year
PubTator Score  0.74

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer