Tdark RFX7 DNA-binding protein RFX7

Protein Summary

Description

RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).[supplied by OMIM, Mar 2009]

Uniprot Accession IDs

• Q2KHR2
• Q6ZRR1
• Q6ZTY6
• Q8N3J0
• Q9H7A9
• Q9H956

Gene Name

• RFX7

Ensembl ID

• ENST00000559447
• ENSP00000453281
• ENSG00000181827

Symbol

• RFXDC2
• RFXDC2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.76
microRNA	0.75
transcription factor binding site profile	0.72
tissue	0.7
interacting protein	0.68

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Transcription Cofactor / Dna-binding Protein Rfx7

Protein / Nucleic Acid Binding / Nuclease / Dna-binding Protein Rfx7

Protein / ... / Winged Helix/forkhead Transcription Factor / Dna-binding Protein Rfx7

DTO Classes

Protein / Enzyme / Nuclease / Dna-binding Protein Rfx7

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.14   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 44   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.14   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0