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Tbio
FAM110C
Protein FAM110C

Protein Summary
Description
May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000327669
  • ENSP00000328347
  • ENSG00000184731
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.77
gene perturbation
0.74
PubMedID
0.69
histone modification site profile
0.64
transcription factor perturbation
0.61


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.51   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.51   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.2
5
attempted suicide
1
1
0
1.2
5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
5
attempted suicide
0
1.2
5
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 110 member C
VGNC:2931
458988
Mouse
MGI:1918813
104943
Rat
RGD:1564713
500638
Chicken
family with sequence similarity 110 member C
CGNC:66167
100859913
Anole lizard
family with sequence similarity 110 member C
100562402
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 110 member C
Mouse
Rat
Chicken
family with sequence similarity 110 member C
Anole lizard
family with sequence similarity 110 member C
Gene Ontology Terms (9)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (16)
1 – 10 of 16
CSPP1
Tbio
Novelty: 0.02734691
Score: 0.93
Data Source: STRINGDB
HIP1R
Tbio
Novelty: 0.02502713
Score: 0.642
Data Source: STRINGDB
SH3YL1
Tdark
Novelty: 0.1550912
Score: 0.634
Data Source: STRINGDB
CNTN5
Tbio
Novelty: 0.00601105
Score: 0.621
Data Source: STRINGDB
ALKAL2
Tbio
Novelty: 0.12969286
Score: 0.602
Data Source: STRINGDB
TMEM47
Tdark
Novelty: 0.1571161
Score: 0.564
Data Source: STRINGDB
LCP1
Tbio
Novelty: 0.0035357
Score: 0.559
Data Source: STRINGDB
PIDD1
Tbio
Novelty: 0.01397556
Score: 0.541
Data Source: STRINGDB
CSNK1E
Tchem
Family: Kinase
Novelty: 0.00891859
Score: 0.514
Data Source: STRINGDB
EDIL3
Tbio
Novelty: 0.00848858
Score: 0.491
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.51

PubMed score by year
PubTator Score  0.75

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer