Tbio LY6K Lymphocyte antigen 6K

Protein Summary

Description

Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth (PubMed:18089789).

Uniprot Accession IDs

• Q17RY6
• G3V116
• O15227
• Q9BVD7
• Ly-6K

Gene Name

• LY6K

Ensembl ID

• ENST00000292430
• ENSP00000292430
• ENSG00000160886
• ENST00000519387
• ENSP00000429695

Symbol

• CO16
• CT97
• ly-6K
• URLC10
• HSJ001348

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.68
cellular component	0.62
cell line	0.53
PubMedID	0.49
transcription factor	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.46   (req: < 5)

Gene RIFs: 14   (req: <= 3)

Antibodies: 100   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.46   (req: >= 5)

Gene RIFs: 14   (req: > 3)

Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0