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Tbio
LY6K
Lymphocyte antigen 6K

Protein Summary
Description
Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth (PubMed:18089789).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000292430
  • ENSP00000292430
  • ENSG00000160886
  • ENST00000519387
  • ENSP00000429695

Symbol
  • CO16
  • CT97
  • ly-6K
  • URLC10
  • HSJ001348
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.68
cellular component
0.62
cell line
0.53
PubMedID
0.49
transcription factor
0.49


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 54.19   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 54.19   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q17RY6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational modification: synthesis of GPI-anchored proteins
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational modification: synthesis of GPI-anchored proteins
Post-translational protein modification
Gene Ontology Terms (5)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (105)
1 – 10 of 105
TEX101
Tbio
Novelty: 0.03488625
Score: 0.974
Data Source: STRINGDB
LY6H
Tbio
Novelty: 0.10210816
Score: 0.971
Data Source: STRINGDB
LYPD2
Tdark
Novelty: 0.55307434
Score: 0.971
Data Source: STRINGDB
LYPD4
Tbio
Novelty: 0.00381728
Score: 0.97
Data Source: STRINGDB
GPIHBP1
Tbio
Novelty: 0.01241227
Score: 0.958
Data Source: STRINGDB
LY6E
Tbio
Novelty: 0.00758512
Score: 0.956
Data Source: STRINGDB
SPACA4
Tdark
Novelty: 0.21569953
Score: 0.955
Data Source: STRINGDB
PSCA
Tbio
Novelty: 0.00323778
Score: 0.954
Data Source: STRINGDB
LY6D
Tbio
Novelty: 0.07032941
Score: 0.944
Data Source: STRINGDB
LYPD5
Tdark
Novelty: 0.97576337
Score: 0.943
Data Source: STRINGDB
Publication Statistics
PubMed Score  54.19

PubMed score by year
PubTator Score  21.6

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer