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Tbio
COL24A1
Collagen alpha-1(XXIV) chain

Protein Summary
Description
May participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development. This gene is a member of the collagen gene family and is thought to regulate type I collagen fibrillogenesis during fetal development. [provided by RefSeq, Mar 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370571
  • ENSP00000359603
  • ENSG00000171502
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.76
cell type or tissue
0.73
histone modification site profile
0.71
cell line
0.69
microRNA
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.1   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.1   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (106)
P3H1
Tbio
Family:  Enzyme
Novelty:  0.02067711
Score:  0.929
Data Source:  STRINGDB
CRTAP
Tbio
Novelty:  0.02380647
Score:  0.924
Data Source:  STRINGDB
COL11A1
Tbio
Novelty:  0.00594683
Score:  0.923
Data Source:  STRINGDB
COL5A1
Tbio
Novelty:  0.00506815
Score:  0.923
Data Source:  STRINGDB
COL5A2
Tbio
Novelty:  0.01352973
Score:  0.922
Data Source:  STRINGDB
COL21A1
Tbio
Novelty:  0.1583142
Score:  0.92
Data Source:  STRINGDB
COL4A3
Tbio
Novelty:  0.00296126
Score:  0.919
Data Source:  STRINGDB
COL4A5
Tbio
Novelty:  0.00283701
Score:  0.919
Data Source:  STRINGDB
COL12A1
Tbio
Novelty:  0.0239421
Score:  0.919
Data Source:  STRINGDB
COL8A1
Tbio
Novelty:  0.02203574
Score:  0.919
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Assembly of collagen fibrils and other multimeric structures (R-HSA-2022090)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Assembly of collagen fibrils and other multimeric structures
Reactome
Collagen biosynthesis and modifying enzymes
Reactome
Collagen chain trimerization
Reactome
Collagen formation
Reactome
Extracellular matrix organization
Name
Explore in Pharos
Explore in Source
Assembly of collagen fibrils and other multimeric structures
Collagen biosynthesis and modifying enzymes
Collagen chain trimerization
Collagen formation
Extracellular matrix organization
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
2
8
8
76.1
intraocular pressure measurement
4
4
4
73
waist-hip ratio
3
4
4
68.1
BMI-adjusted waist-hip ratio
2
2
2
65.3
waist circumference
1
2
2
54.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
8
76.1
intraocular pressure measurement
4
73
waist-hip ratio
4
68.1
BMI-adjusted waist-hip ratio
2
65.3
waist circumference
2
54.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1918605
71355
Rat
RGD:1565539
499723
Dog
collagen type XXIV alpha 1 chain
VGNC:39469
479965
Horse
collagen type XXIV alpha 1 chain
VGNC:16735
100063903
Chicken
collagen type XXIV alpha 1 chain
CGNC:52211
424526
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
collagen type XXIV alpha 1 chain
Horse
collagen type XXIV alpha 1 chain
Chicken
collagen type XXIV alpha 1 chain
Publication Statistics
PubMed Score 7.10
PubMed score by year
PubTator Score 0.77
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title